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Gene Expression Data
Assay Details
Assay
Reference: J:37752 Parker SB, et al., p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells [see comments]. Science. 1995 Feb 17;267(5200):1024-7
Assay type: RNA in situ
MGI Accession ID: MGI:5465305
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Probe: p21 cDNA3
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 7.5 (more )
Note: 0-5 somites.
Structure Level Pattern Image Note
TS12: embryo Absent
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural tube Present Regionally restricted Expressed along the midline.
TS13: hindgut diverticulum Present
Specimen 1A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: somite Present Regionally restricted 1A Expressed in the dermomyotome. No expression in the presomitic paraxial mesoderm.
Specimen 1B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: myotome Strong Regionally restricted 1B Expressed in the muscle fibers extending from the anterior to the posterior margin.
Specimen 1D: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 1D Expressed in the dorsal region, representing the emerging dorsal muscle mass. No expression in the ventral muscle mass.
Specimen 1F: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: dermomyotome Present 1F
TS16: forelimb bud apical ectodermal ridge Present 1F
Specimen 1H/K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present 1K , 1H
TS23: forelimb Present 1K , 1H
TS23: forelimb pre-cartilage condensation Present 1H
Specimen 1I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: body wall Strong Regionally restricted 1I Expressed in the intercostal muscle.
TS20: rib pre-cartilage condensation Strong 1I
Specimen 1L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nasal cavity epithelium Present 1L
TS20: tongue muscle Present 1L
Specimen 1N: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hair follicle Present 1N
TS23: nasal cavity respiratory epithelium Present Widespread 1N
TS23: olfactory epithelium Present Regionally restricted 1N Expressed in the layer containing differentiating olfactory neurons. No expression in the mitotic germinal layer.
Specimen 2Aa: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: somite Present 2Aa
Specimen 2Ac: embryonic day 11.5; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS19: somite Present 2Ac
Specimen 2Ad: embryonic day 13.5; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS21: nasal cavity epithelium Present 2Ad
TS21: tongue muscle Present 2Ad
Specimen 2Ae: embryonic day 13.5; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS21: vertebral axis musculature Strong Regionally restricted 2Ae Expressed in the intercostal muscle.
TS21: forelimb musculature Present 2Ae
TS21: forelimb pre-cartilage condensation Present 2Ae
Specimen 2Ba: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 2Ba Expressed in the fully differentiated columnar epithelium.
Specimen 2Bb: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: stomach epithelium Present Regionally restricted 2Bb Expressed in the fully differentiated columnar epithelium.
Specimen 2Bc: postnatal month 4; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS28: small intestine epithelium Present Regionally restricted 2Bc Expression is unaltered in mutant mice. Expressed in the fully differentiated columnar epithelium.
Specimen 2Bd: postnatal month 4; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS28: stomach epithelium Present Regionally restricted 2Bd Expression is unaltered in mutant mice. Expressed in the fully differentiated columnar epithelium.
Specimen 2Be: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: lung Present Uniform 2Be
Specimen 2Bf: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: liver Present Uniform 2Bf
Specimen 2Bg: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: limb musculature Present Uniform 2Bg
Specimen 2Bh: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 2Bh
Specimen 2Bi: postnatal month 4; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS28: lung Present Uniform 2Bi Expression is unaltered in mutant mice.
Specimen 2Bj: postnatal month 4; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS28: liver Present Uniform 2Bj Expression is unaltered in mutant mice.
Specimen 2Bk: postnatal month 4; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS28: limb musculature Present Uniform 2Bk Expression is unaltered in mutant mice.
Specimen 2Bl: postnatal month 4; Trp53tm1Brd/Trp53tm1Brd (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 2Bl Expression is unaltered in mutant mice.
Specimen 4Aa: embryonic day 15.5; Myogtm1Whk/Myogtm1Whk (more )
Structure Level Pattern Image Note
TS23: hair follicle Present 4Aa Expression was retained in mutant mice.
TS23: nasal cavity epithelium Present 4Aa Expression was retained in mutant mice.
TS23: nasal cavity respiratory epithelium Present 4Aa Expression was retained in mutant mice.
TS23: tongue muscle Present 4Aa Expression was retained in mutant mice.
TS23: musculature Present 4Aa Expression was retained in mutant mice. Expressed in other muscle tissue at this section level.
Specimen 4Ac: embryonic day 15.5; Myogtm1Whk/Myogtm1Whk (more )
Structure Level Pattern Image Note
TS23: forelimb musculature Present 4Ac Expression was retained in mutant mice.
TS23: musculature Present 4Ac Expression was retained in mutant mice. Expressed in other muscle tissue at this section level.
Specimen 4Ba: embryonic day 14.0; Myod1tm1Jae/Myod1tm1Jae, Myogtm1Whk/Myogtm1Whk (more )
Structure Level Pattern Image Note
TS22: tongue muscle Present 4Ba Expression is comparable to that found in wild-type animals.
Specimen 4Bb: embryonic day 14.0; Myod1tm1Jae/Myod1tm1Jae, Myogtm1Whk/Myogtm1Whk (more )
Structure Level Pattern Image Note
TS22: forelimb Present 4Bb Expression is comparable to that found in wild-type animals.
TS22: forelimb musculature Present 4Bb Expression is comparable to that found in wild-type animals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory