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Gene Expression Data
Assay Details
Assay
Reference: J:2959 Price M, et al., Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain. Neuron. 1992 Feb;8(2):241-55
Assay type: RNA in situ
MGI Accession ID: MGI:5462556
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: TTF1 probe1
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Present Regionally restricted 4C Expression was detected in the posterior area.
TS20: corpus striatum Present Regionally restricted 4C Expression was detected in the median corpus striatum.

Specimen 5A TTF-1: embryonic day 10.0 (more )
Note: Section pseudocolored and overlaid with other expression patterns. Colors: green - Nkx2-1; blue - Dlx1 (assay MGI:5462557); red - Nkx2-2 (assay MGI:5462555).
Structure Level Pattern Image Note
TS16: diencephalon Present 6C , 6A merge , 5A TTF1 , 6B , 6D/E , 6A TTF-1 Expression was detected throughout the neuroepithelium.

Specimen 5B TTF-1: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 5B TTF1 Expression was detected throughout the walls of the posterior hypothalamus.

Specimen 6F/G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: diencephalon Present Regionally restricted 6F/G Expression was detected throughout the neuroepithelium.

Specimen 7A TTF-1: embryonic day 12.5 (more )
Note: Fig. 7 shows a frontal series of sections through the forebrain, with A being more anterior and D more posterior.
Structure Level Pattern Image Note
TS20: thalamus Absent 7A TTF1

Specimen 7B TTF-1: embryonic day 12.5 (more )
Note: Fig. 7 shows a frontal series of sections through the forebrain, with A being more anterior and D more posterior.
Structure Level Pattern Image Note
TS20: thalamus Absent 7B TTF1
TS20: hypothalamus Present Regionally restricted 7B TTF1 Expression was detected in posterior hypothalamus.

Specimen 7C TTF-1: embryonic day 12.5 (more )
Note: Fig. 7 shows a frontal series of sections through the forebrain, with A being more anterior and D more posterior.
Structure Level Pattern Image Note
TS20: thalamus Absent 7C TTF1
TS20: hypothalamus Present Regionally restricted 7C TTF1 Expression was detected in the floor of posterior hypothalamus.

Specimen 7D TTF-1: embryonic day 12.5 (more )
Note: Fig. 7 shows a frontal series of sections through the forebrain, with A being more anterior and D more posterior.
Structure Level Pattern Image Note
TS20: diencephalon Strong 7D TTF1

Specimen 9A TTF-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hypothalamus Strong Regionally restricted 9A TTF1 Expression was detected in ventral hypothalamus.

Specimen 9B TTF-1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 9B TTF1 Expression was detected in the ependymal layer.
TS22: hypothalamus Present Regionally restricted 9B TTF1 Expression was weak in the ependyma, but was strong in the most dorsal hypothalamic area.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory