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Gene Expression Data
Assay Details
Assay
Reference: J:42463 Chotteau-Lelievre A, et al., Differential expression patterns of the PEA3 group transcription factors through murine embryonic development. Oncogene. 1997 Aug 18;15(8):937-52
Assay type: RNA in situ
MGI Accession ID: MGI:5462442
Gene symbol: Etv4
Gene name: ets variant 4
Probe: Pea3 probe
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 5C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dental papilla Strong 5C
TS23: dorsal root ganglion Strong 5C
TS23: jaw Present 5C
TS23: tongue Present 5C
TS23: trachea cartilaginous ring Present 5C
TS23: skeletal muscle Present Regionally restricted 5C Expression in neck muscles.
TS23: appendicular skeleton Present Regionally restricted 5C Expression in young aggregating chondroblasts but not in cartilage matrix.
TS23: salivary gland Strong Regionally restricted 5C High expression in bulbous epithelial lobules, composed of epithelial cells surrounded by condensed mesenchymal cells. No expression in the more differentiated epithelial stalks.

Specimen 6D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Weak 6D Expression in both the neural layer of the retina and in the lens.
TS17: optic cup Weak 6D Expression in both the neural layer of the retina and in the lens.

Specimen 7D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: retina nuclear layer Weak 7D
TS23: optic choroid Present 7D

Specimen 8D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: olfactory epithelium Present Regionally restricted 8D Expression in both the neural layer of the retina and in the lens.
TS23: nose Present Regionally restricted 8D Homogenous expression in mesenchyme adjacent to the olfactory vesicle.
TS23: nasal capsule Present Regionally restricted 8D Expression in perichondrial cells lining newly formed cartilage of nasal capsule and septum.
TS23: nasal septum Present Regionally restricted 8D Expression in perichondrial cells lining newly formed cartilage of nasal capsule and septum.

Specimen 9D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: adenohypophysis Present 9D
TS23: neurohypophysis infundibulum Present 9D

Specimen 10C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mammary gland primordium epithelium Strong 10C
TS23: skeletal muscle Present Regionally restricted 10C Expression in perichondrial cells lining newly formed cartilage of nasal capsule and septum.
TS23: appendicular skeleton Present Regionally restricted 10C Expression in young aggregating chondroblasts but not in cartilage matrix
TS23: atrium cardiac muscle Weak 10C
TS23: lung epithelium Weak 10C
TS23: lung mesenchyme Weak 10C
TS23: ventricle cardiac muscle Weak 10C

Specimen 11C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube floor plate Present 11C
TS17: dermomyotome Present Regionally restricted 11C Expression in the lateral dermomyotome and adjacent sclerotomal cells.
TS17: sclerotome Present Regionally restricted 11C Expression in the lateral dermomyotome and adjacent sclerotomal cells.

Specimen 12D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: gut mesenchyme Present Regionally restricted 12D Expression in differentiating mesodermal layers surrounding the tracheal and digestive tract.
TS23: gut epithelium Present Regionally restricted 12D Expression in the basal layers of endodermal epithelium.

Specimen 13D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Strong Regionally restricted 13D Expression in distal mesenchymal cells correponding to the progress zone.
TS19: apical ectodermal ridge Strong 13D

Specimen 14C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: ureteral mesenchyme Present Regionally restricted 14C Expression in the ureteric epithelium and surrounding mesenchymal condensation.
TS23: urothelium of ureter Present Regionally restricted 14C Expression in the ureteric epithelium and surrounding mesenchymal condensation.

Specimen 15D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 15D Expression in epithelial cells of the capsule located in the periphery of the gland.

Specimen not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung epithelium Present

Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present
TS21: tooth mesenchyme Present
TS21: neural retinal epithelium Weak

Specimen not shown E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: thyroid gland Present Regionally restricted Expression in the epithelial cells of the peripheral capsule.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory