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Gene Expression Data
Assay Details
Assay
Reference: J:37125 Serafini T, et al., Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell. 1996 Dec 13;87(6):1001-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5462090
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-NF-M (3A10)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5A: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 5A
Specimen 5B: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 5B Spinal cords of mutant embryos (six embryos examined) display apparently normal neuronal positioning and axonal trajectories as compared to heterozygote embryos except for the lack of a ventrally directed commissural projection.
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cranial nerve Present 6A Shown are trochlear motoneurons.
Specimen 6B: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Structure Level Pattern Image Note
TS17: cranial nerve Present 6B Shown are trochlear motoneurons.
Specimen 6C: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg (more )
Structure Level Pattern Image Note
TS17: cranial nerve Present 6C Shown are trochlear motoneurons and mutants show no obvious defects in trochlear axon trajectories.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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