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Gene Expression Data
Assay Details
Assay
Reference: J:40837 Mitsiadis TA, et al., Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4. Development. 1997 Apr;124(8):1473-83
Assay type: RNA in situ
MGI Accession ID: MGI:5461954
Gene symbol: Jag1
Gene name: jagged 1
Probe: Ser-1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo endoderm Present Regionally restricted 1A Expressed in a small area around the primitive streak, presumably in embryonic endoderm.

Specimen 1B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: rhombomere 1 Strong 1B High expression in two transverse stripes, and lower levels in a third, more posterior stripe.
TS13: rhombomere 3 Strong 1B High expression in two transverse stripes, and lower levels in a third, more posterior stripe.
TS13: rhombomere 5 Present 1B

Specimen 1C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Strong Regionally restricted 1C Intense expression in a region between the first and second branchial arches, and the area just posterior of the second branchial arch.
TS15: otocyst Strong 1C Intense expression in the otic vesicle.

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 1 Absent
TS15: rhombomere 3 Absent
TS15: rhombomere 5 Absent

Specimen 1D: embryonic day 8.5 (more )
Note: This embryo has 6 somites. Double labeled: blue - Jag1 (Ser-1); brown - Egr2 (Krox-20; assay MGI:5462080).
Structure Level Pattern Image Note
TS12: rhombomere Present Regionally restricted 1D Expressed in 3 stripes corresponding to the presumptive rhombomere 1, 3 and 5.

Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: mesonephros Present 1E Expressed in pronephros.
TS15: somite Present Regionally restricted 1E Expressed in a thin stripe of cells in the forming somite boundary.

Specimen 1F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 1F
TS19: limb Present 1F
TS19: maxillary process Present 1F
TS19: midbrain Present 1F

Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Regionally restricted 1G Expressed in the epithelium.
TS19: hindlimb bud mesenchyme Present Regionally restricted 1G Expressed in the most distal part of the mesenchyme.

Specimen 3 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present 3_Serrate-1 E12.5

Specimen 3 DRG: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 3_Serrate-1 DRG

Specimen 3 max. proc.: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: maxillary process Present 3_Serrate-1 max. proc.

Specimen 3 aorta: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal aorta Present 3_Serrate-1 aorta

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Present

Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: mesonephros Present Regionally restricted 4A Expressed in epithelial tubules.

Specimen 4B: embryonic day 13.5-14.5 (more )
Structure Level Pattern Image Note
TS22: maturing glomerular tuft Present 4B
TS22: mesenchyme of metanephros Absent 4B

Specimen 4C: embryonic day 15.5-16.5 (more )
Structure Level Pattern Image Note
TS23: maturing glomerular tuft Present 4C
TS23: adrenal gland Absent 4C
TS23: mesenchyme of metanephros Absent 4C

Specimen 4D: embryonic day 15.5-16.5 (more )
Structure Level Pattern Image Note
TS23: maturing glomerular tuft Present 4D
TS23: mesenchyme of metanephros Absent 4D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory