Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Stx11tm1Bupa
Name:	syntaxin 11; targeted mutation 1, Silvia Bulfone-Paus
MGI ID:	MGI:5461477
Gene:	Stx11  Location: Chr10:12813953-12840042 bp, - strand  Genetic Position: Chr10, 4.54 cM, cytoband A2
Alliance:	Stx11tm1Bupa page

Germline Transmission:	Earliest citation of germline transmission: J:191103
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A PGK-neomycin selection cassette replaced the entire coding exon. (J:191103)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stx11 Mutation:	7 strains or lines available

Original:	J:191103 D'Orlando O, et al., Syntaxin 11 is required for NK and CD8(+) T-cell cytotoxicity and neutrophil degranulation. Eur J Immunol. 2013 Jan;43(1):194-208
All:	2 reference(s)