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Gene Expression Data
Assay Details
Assay
Reference: J:164032 Mayer M, et al., Expression of two type II cadherins, Cdh12 and Cdh22 in the developing and adult mouse brain. Gene Expr Patterns. 2010 October - December;10(7-8):351-360
Assay type: RNA in situ
MGI Accession ID: MGI:5461049
Gene symbol: Cdh12
Gene name: cadherin 12
Probe: Cdh12 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3A Expression is in the lateral entorhinal cortex.
TS22: thalamus Present Regionally restricted 3A Expression is in the forming ventromedial thalamic nuclei.

Specimen 3C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epithalamus Present Regionally restricted 3C Expression is in the medial habenula.

Specimen 3E: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: thalamus Strong Regionally restricted 3E Expression is in the ventromedial thalamic nuclei.

Specimen 3G: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: thalamic nucleus Strong Regionally restricted 3G Expression is in dorsolateral and ventromedial thalamic nuclei.
TS27: medial habenular nucleus Weak Regionally restricted 3G

Specimen 3I: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: epithalamus Present Regionally restricted 3I Expression is lateral.

Specimen 3K: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: thalamus Present 3K Expression is in the forming thalamic nuclei.

Specimen 3M: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epithalamus Weak Regionally restricted 3M Expression is in the lateral habenula and is dorsal in the medial habenula.

Specimen 3O: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Present Regionally restricted 3O Expresion is in the anterior hypothalamic nucleus.

Specimen 3Q: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: thalamus Strong Regionally restricted 3Q Expression is in the ventromedial thalamic nuclei.
TS26: epithalamus Absent 3Q Absent in the ventral habenular nuclei.

Specimen 3S: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: hypothalamus Weak Regionally restricted 3S Expression is in the dorsomedial nuclei, absent in the lateral hypothalamic nuclei.

Specimen 3U: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: medial habenular nucleus Weak 3U
TS27: thalamus Present Regionally restricted 3U Dorsolateral thalamus.
TS27: thalamic nucleus Strong Regionally restricted 3U Expression is in dorsolateral and ventromedial thalamic nuclei.

Specimen 3X: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: basolateral amygdaloid nucleus Weak 3X
TS27: dorsomedial hypothalamic nucleus Weak 3X
TS27: central amygdaloid nucleus Absent 3X

Specimen 4A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 4A Expression is in almost all areas except the reticular nucleus.
TS28: lateral geniculate nucleus Present 4A
TS28: medial geniculate nucleus Present 4A
TS28: zona incerta Present 4A
TS28: reticular thalamic nucleus Absent 4A

Specimen 4C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 4C Expression is in almost all areas except the reticular nucleus.
TS28: hypothalamic nucleus Present Regionally restricted 4C Absent in the central part of the nucleus in the ventromedial hypothalamus.
TS28: reticular thalamic nucleus Absent 4C

Specimen 4E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 4E Expression is in almost all areas except the reticular nucleus.
TS28: medial habenular nucleus Present 4E
TS28: reticular thalamic nucleus Absent 4E

Specimen 4G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hypothalamus Present Regionally restricted 4G Expression is in the dorsomedial and lateral part of the ventromedial hypothalamus.
TS28: hypothalamic nucleus Present Regionally restricted 4G Absent in the central part of the nucleus in the ventromedial hypothalamus.

Specimen 4H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Present Regionally restricted 4H Levels are significantly higher in the lateral part and much lower in central and medial nuclei.

Specimen 4K: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4K
TS28: cerebellum granule cell layer Present Regionally restricted 4K Expression is in Golgi cells.

Specimen 4L: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal cochlear nucleus Present Scattered 4L
TS28: deep cerebellar nucleus Present Regionally restricted 4L Expression is in scattered cells of the dentate nucleus.
TS28: trigeminal nucleus Present 4L

Specimen Not shown E14.0: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: hippocampus Absent

Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 5A Expression is in the future pyramidal cells of the CA1-CA3 regions, in scattered cells of the strata oriens, radiatum and lacunosum-moleculare of CA1, and in the hilus of the dentate gyrus.

Specimen 5B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus layer Present 5B
TS27: dentate gyrus granule cell layer Weak 5B

Specimen 5C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Strong 5C
TS28: hippocampus region Strong Regionally restricted 5C Expression is in pyramidal cells.

Specimen 5G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Strong 5G
TS28: CA1 pyramidal cell layer Strong 5G
TS28: hippocampus CA3 Strong Regionally restricted 5G Expression is in pyramidal cells.

Specimen 5H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus region Present Regionally restricted 5H Expression is in pyramidal cells.

Specimen 5I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Strong 5I
TS28: dentate gyrus granule cell layer Strong 5I
TS28: hippocampus CA3 Strong Regionally restricted 5I Expression is in pyramidal cells.

Specimen 5N: postnatal adult (more )
Note: Double labeled: purple - Cdh12; orange - Slc17a7 (Vglut1; assay MGI:5461531).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 5N

Specimen 5O: postnatal adult (more )
Note: Double labeled: purple - Cdh12; orange - Slc17a7 (Vglut1; assay MGI:5461531).
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5O

Specimen 5Q: postnatal adult (more )
Note: Double labeled: purple - Cdh12; orange - Gad1 (assay MGI:5461530).
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 5Q

Specimen 5R: postnatal adult (more )
Note: Double labeled: purple - Cdh12; orange - Gad1 (assay MGI:5461530).
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5R

Specimen 6A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cortical plate Present Regionally restricted 6A Expression is throughout the outer and in scattered cells in the deeper part of the cortical plate.

Specimen 6B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical layer III Strong 6B
TS27: cortical layer V Strong 6B

Specimen 6C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cortical layer II Strong 6C
TS27: cortical layer III Strong 6C
TS27: cortical layer V Strong 6C

Specimen 6D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted 6D About 80% of these layers is labeled on the ventricular side.
TS28: cortical layer III Present Regionally restricted 6D About 80% of these layers is labeled on the ventricular side.
TS28: cortical layer V Present 6D
TS28: cortical layer VI Present 6D

Specimen 6I: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present 6I

Specimen 6K: postnatal day 7 (more )
Note: Double labeled: purple - Cdh12; orange - Cux2 (assay MGI:5461532).
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted 6K Labeling is on the ventricular side.
TS28: cortical layer III Present Regionally restricted 6K Labeling is on the ventricular side.
TS28: cortical layer V Present 6K

Specimen 6L: postnatal day 7 (more )
Note: Double labeled: purple - Cdh12; orange - Cux2 (assay MGI:5461532).
Structure Level Pattern Image Note
TS28: cortical layer II Present Regionally restricted 6L Labeling is on the ventricular side.
TS28: cortical layer III Present Regionally restricted 6L Labeling is on the ventricular side.

Specimen 6O: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present 6O

Specimen 6P: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present 6P


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory