About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:73821 Feige E, et al., The related murine kinases, Nek6 and Nek7, display distinct patterns of expression. Mech Dev. 2002 Jan;110(1-2):219-23
Assay type: RNA in situ
MGI Accession ID: MGI:5460831
Gene symbol: Nek6
Gene name: NIMA (never in mitosis gene a)-related expressed kinase 6
Probe: Nek6 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1B: embryonic day 6.75 (more )
Structure Level Pattern Image Note
TS10: primary trophoblast giant cell Strong 1B Highest levels of expression in primary trophoblast giant cells surrounding the embryo.

Specimen 1B maternal: embryonic day 6.75 (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 1B Lower levels in periphery of maternal decidua, but not in decidual cells surrounding the implantation region.

Specimen 1F: embryonic day 8.5-8.75 (more )
Structure Level Pattern Image Note
TS14: ectoplacental cone Strong 1F
TS14: chorionic plate Absent 1F

Specimen not shown E8.5: embryonic day 8.5-8.75 (more )
Structure Level Pattern Image Note
TS14: allantois Absent

Specimen not shown maternal: embryonic day 8.5-8.75 (more )
Structure Level Pattern Image Note
TS28: decidua Weak Regionally restricted Lower levels in periphery of maternal decidua, but not in decidual cells surrounding the implantation region.

Specimen 1J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Strong 1J
TS20: trophoblast giant cell Absent 1J No expression in secondary giant trophoblast cells forming the interface with the maternal decidua.
TS20: labyrinthine zone Absent 1J

Specimen not shown E6.5: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo Weak Uniform Low and homogeneous pattern of expression.

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Weak Uniform Low and homogeneous pattern of expression.

Specimen not shown E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: septum transversum Present

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain subventricular zone Present 2B
TS21: brain ventricular layer Present 2B

Specimen 2D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain subventricular zone Present 2D
TS26: brain ventricular layer Present 2D

Specimen not shown E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: spinal cord Present Regionally restricted Low and homogeneous pattern of expression.

Specimen 2F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine epithelium Present 2F

Specimen not shown adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: intestine epithelium Present

Specimen 3B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Weak 3B
TS28: main olfactory bulb mitral cell layer Weak 3B

Specimen 3D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: parietal cortex Absent 3D

Specimen 3F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: piriform cortex Strong 3F

Specimen 3G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 3G
TS28: hippocampus CA3 Strong 3G
TS28: entorhinal cortex Present 3G
TS28: hippocampus CA1 Present 3G
TS28: hippocampus CA2 Present 3G

Specimen 3I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Present 3I

Specimen 3J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 3J

Specimen Table 1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hindbrain Weak Regionally restricted Low level expression in several ventral nuclei.
TS28: periolivary nucleus Weak Scattered
TS28: superior olivary nucleus Weak Scattered
TS28: trigeminal V sensory nucleus Weak Scattered

Specimen 3O: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ovary antral follicle Strong Regionally restricted 3O High levels of expression restricted to granulosa cells of large growing and antral follicles
TS28: ovary growing follicle Strong Regionally restricted 3O High levels of expression restricted to granulosa cells of large growing and antral follicles
TS28: ovary stratum granulosum Strong Regionally restricted 3O High levels of expression restricted to granulosa cells of large growing and antral follicles

Specimen not shown testis: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory