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Gene Expression Data
Assay Details
Assay
Reference: J:148798 Furusawa T, et al., Expression of nucleosomal protein HMGN1 in the cycling mouse hair follicle. Gene Expr Patterns. 2009 Jun;9(5):289-95
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5449864
Gene symbol: Hmgn1
Gene name: high mobility group nucleosomal binding domain 1
Antibody: HMGN1 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C,E: postnatal newborn (more )
Note: Stage 2 of hair follicle development. Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 1E , 1C Expression is in the epidermal placode at stage 2 of hair follicle development.
TS27: dermis Present Regionally restricted 1E , 1C Expression is in the dermal condensate stage 2 of hair follicle development.
Specimen 1G,I: postnatal newborn (more )
Note: Stage 3 of hair follicle development. Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS27: dermis Present Regionally restricted 1I , 1G Expression is in the dermal papilla in stage 3 of hair follicle development.
TS27: coat hair follicle Present Regionally restricted 1I , 1G Absent in hair germ in stage 3 of hair follicle development.
Specimen 1K,M: postnatal newborn (more )
Note: Stage 4 of hair follicle development. Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS27: dermis Present Regionally restricted 1M , 1K Expression is in the dermal papilla in stage 4 of hair follicle development.
TS27: coat hair follicle Present Regionally restricted 1M , 1K Expression is in the hair matrix in stage 4 of hair follicle development.
Specimen 2A,C: postnatal adult (more )
Note: Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS28: epidermis basal layer Present Regionally restricted 2A , 2C
Specimen 2E,G: postnatal adult (more )
Note: Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS28: hair outer root sheath Present Regionally restricted 2G , 2E
Specimen 2I,K: postnatal adult (more )
Note: Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS28: hair outer root sheath Present Regionally restricted 2I , 2K
Specimen 2M,O: postnatal adult (more )
Note: Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 2M , 2O Expression is in the dermal papilla and the matrix region.
Specimen 3A: postnatal (more )
Note: Double labeled: green - Hmgn1; red - Nes (assay MGI:5449876).
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 3A
TS28: sebaceous gland Present 3A
TS28: hair inner root sheath Absent 3A
Specimen 3C: postnatal (more )
Note: Double labeled: green - Hmgn1; red - Nes (assay MGI:5449876).
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 3C
TS28: sebaceous gland Present 3C
TS28: hair inner root sheath Absent 3C
Specimen 3E,G: postnatal (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 3G , 3E
Specimen 3I,K: postnatal (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 3I , 3K
Specimen 4B: postnatal (more )
Note: Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS28: epidermis Strong 4B
TS28: hair outer root sheath Strong 4B
Specimen 4E: postnatal; Hmgn1tm1Mbus/Hmgn1tm1Mbus (more )
Note: Double labeled: green - Hmgn1; red - Trp63 (assay MGI:5449873).
Structure Level Pattern Image Note
TS28: epidermis Absent 4E
TS28: hair outer root sheath Absent 4E
Specimen 4G: postnatal (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 4G
TS28: sebaceous gland Present 4G
TS28: hair inner root sheath Absent 4G
Specimen 4J: postnatal; Hmgn1tm1Mbus/Hmgn1tm1Mbus (more )
Structure Level Pattern Image Note
TS28: hair inner root sheath Absent 4J
TS28: hair outer root sheath Absent 4J
TS28: sebaceous gland Absent 4J
Specimen S1A: postnatal (more )
Note: Catagen hair follicle.
Structure Level Pattern Image Note
TS28: epidermis basal layer Present S1A
TS28: hair outer root sheath Present S1A
Specimen S1D: postnatal (more )
Note: Catagen hair follicle.
Structure Level Pattern Image Note
TS28: coat hair follicle Strong Regionally restricted S1D Expression is in the dermal papilla and weakly in the epithelial strand.
Specimen S1G: postnatal (more )
Note: Telogen hair follicle.
Structure Level Pattern Image Note
TS28: epidermis Strong S1G
TS28: hair outer root sheath Strong S1G
TS28: sebaceous gland Strong S1G
TS28: coat hair follicle Weak Regionally restricted S1G Expression is in the dermal papilla.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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