Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dcktm1.2Radu
Name:	deoxycytidine kinase; targeted mutation 1.2, Caius G Radu
MGI ID:	MGI:5449592
Synonyms:	Dckflox
Gene:	Dck  Location: Chr5:88912872-88931136 bp, + strand  Genetic Position: Chr5, 43.96 cM, cytoband E2
Alliance:	Dcktm1.2Radu page

Germline Transmission:	Earliest citation of germline transmission: J:158373
Parent Cell Line:	LW1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert a loxP sites flanking exon 3, followed by a frt-flanked neomycin resistance (neo) cassette. Flp-mediated recombination remvoed the neo cassette and left exon 3 floxed. (J:158373)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dck Mutation:	20 strains or lines available

Original:	J:158373 Toy G, et al., Requirement for deoxycytidine kinase in T and B lymphocyte development. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5551-6
All:	2 reference(s)