Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Akap5tm1Mdaq
Name:	A kinase anchor protein 5; targeted mutation 1, Mark Dell'Acqua
MGI ID:	MGI:5448682
Synonyms:	AKAP150deltaPIX, Akap5tm2Jsco
Gene:	Akap5  Location: Chr12:76371665-76380927 bp, + strand  Genetic Position: Chr12, 33.73 cM
Alliance:	Akap5tm1Mdaq page

Germline Transmission:	Earliest citation of germline transmission: J:190017
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	(C57BL/6 x 129)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The 21 bp sequence in the coding exon containing the conserved PIAIIIT motif (amino acids 655 to 661) was removed. A floxed neo cassette was inserted downstream of the modified coding exon. (J:190017)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Akap5 Mutation:	27 strains or lines available

Original:	J:190017 Hinke SA, et al., Anchored phosphatases modulate glucose homeostasis. EMBO J. 2012 Oct 17;31(20):3991-4004
All:	7 reference(s)