Gene Expression Data
Assay Details
Assay
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Reference:
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J:130176
Nammo T, et al., Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas. Gene Expr Patterns. 2008 Jan;8(2):96-106
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5448228
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Gene symbol:
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Hnf4a
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Gene name:
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hepatic nuclear factor 4, alpha
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Antibody:
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anti-HNF4a (clone H1415)
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
1A:
embryonic day 9.5
(more )
Specimen
1A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS15: pancreas primordium |
Present |
Regionally restricted |
1A
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Expression in most epithelial cells of the pancreatic bud. Constant level of expression in most pancreatic cells; strong expression in a few cells.
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Specimen
1B:
embryonic day 10.5
(more )
Specimen
1B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS17: pancreas primordium |
Present |
Non-Uniform |
1B
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Constant level of expression in most pancreatic cells; strong expression in a few cells.
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Specimen
1C:
embryonic day 11.5
(more )
Specimen
1C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: pancreas primordium |
Present |
Regionally restricted |
1C
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Constant level of expression in most pancreatic cells; strong expression in a few cells. Expresssion was more intense by E11.5.
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Specimen
1D:
embryonic day 12.5
(more )
Specimen
1D:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS20: pancreas |
Present |
Regionally restricted |
1D
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Constant level of expression in most pancreatic cells; strong expression in a few cells. Expression in cells with branching epithelial structures.
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Specimen
1E:
embryonic day 14.5
(more )
Specimen
1E:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS22: pancreas |
Present |
Regionally restricted |
1E
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Constant level of expression in most pancreatic cells; strong expression in a few cells. Expression in cells with branching epithelial structures.
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Specimen
1F:
embryonic day 15.5
(more )
Specimen
1F:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS23: pancreas |
Present |
Regionally restricted |
1F
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Strong expression in differentiated acinar cells with a polarized appearance; weak expression in duct-like epithelium. Strong expression in a few cells within islet-like cell clusters.
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Specimen
1G:
embryonic day 16.5
(more )
Specimen
1G:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS24: pancreas |
Present |
Regionally restricted |
1G
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Strong expression in differentiated acinar cells with a polarized appearance; weak expression in duct-like epithelium. Strong expression in a few cells within islet-like cell clusters.
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Specimen
1H:
embryonic day 17.5
(more )
Specimen
1H:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS25: pancreas |
Present |
Regionally restricted |
1H
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Weak expression in ductal cells and most of the islet cells. Strong expression in a few cells located at the periphery of the islets.
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Specimen
1I:
postnatal day 10
(more )
Specimen
1I:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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