Tg(Rho-GUCA1B)1Jnc
Transgene Detail
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Symbol: |
Tg(Rho-GUCA1B)1Jnc |
Name: |
transgene insertion 1, Jeannie Chen |
MGI ID: |
MGI:2664161 |
Transgene: |
Tg(Rho-GUCA1B)1Jnc Location: unknown
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Alliance: |
Tg(Rho-GUCA1B)1Jnc page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Rho-GUCA1B)1Jnc expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
cattle |
GUCA1B (286851) |
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Mutation details: A 0.7 kb cDNA fragment encoding the bovine GUCA1B was adjoined to a 4.4 kb murine rhodopsin promoter and a polyadenylation signal from the murine Prm1 locus. Expression of the bovine GUCA1B was approximately 2-fold higher than that of the endogenous murine Guca1B. The pattern of retinal expression was shown to be similar to that of murine Guca1b by Indirect immunofluorescent labeling.
(J:83914)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:83914 Mendez A, et al., Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9948-53 |
All: |
2 reference(s) |
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