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Tg(Rho-GUCA1B)1Jnc
Transgene Detail
Summary
Symbol: Tg(Rho-GUCA1B)1Jnc
Name: transgene insertion 1, Jeannie Chen
MGI ID: MGI:2664161
Transgene: Tg(Rho-GUCA1B)1Jnc  Location: unknown  
Alliance: Tg(Rho-GUCA1B)1Jnc page
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Rho-GUCA1B)1Jnc expresses 1 gene
 
Mutation detailsA 0.7 kb cDNA fragment encoding the bovine GUCA1B was adjoined to a 4.4 kb murine rhodopsin promoter and a polyadenylation signal from the murine Prm1 locus. Expression of the bovine GUCA1B was approximately 2-fold higher than that of the endogenous murine Guca1B. The pattern of retinal expression was shown to be similar to that of murine Guca1b by Indirect immunofluorescent labeling. (J:83914)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:83914 Mendez A, et al., Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9948-53
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory