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Gene Expression Data
Assay Details
Assay
Reference: J:57797 Rogers JH, et al., Eph receptors and ephrins demarcate cerebellar lobules before and during their formation. Mech Dev. 1999 Sep;87(1-2):119-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5447359
Gene symbol: Epha7
Gene name: Eph receptor A7
Antibody: EphA7 antibody
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum dorsal part Present Regionally restricted 2B Expression restricted to a dorsal patch; band right across the cerebellum; appeared to prefigure lobule VI and/or VII.

Specimen not shown: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present Regionally restricted Authors state that eexpression was down-regulated in the medial cerebellum in some P1 specimens.

Specimen 4D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present Regionally restricted 4D Expression in diagonal fibers connecting lobule VII with the brainstem.
TS27: cerebellum vermis lobule VII Present Regionally restricted 4D Expression in neuropil of the molecular layer and Purkinje cell layer in lobule VII.
TS27: cerebellum vermis lobule VI Present Regionally restricted 4D Authors report similar expression in lobule VI.

Specimen 5B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellar cortex Present Regionally restricted 5B Expression in lateral parts of the cerebellar cortex, correponding to lobulus simplex (lobule VI).
TS27: cerebellum vermis lobule VI Present Regionally restricted 5B Expression in lateral parts of the cerebellar cortex, correponding to lobulus simplex (lobule VI).
TS27: cerebellum vermis lobule VII Present Regionally restricted 5B Expression in lateral parts of the cerebellar cortex, correponding to Crus 2 (lateral extension of lobule VII-posterior. Expression in the sulci separating them from the intervening Crus 1. Weak expression in Crus 1.
TS27: cerebellar hemisphere Present Regionally restricted 5B No expression in paraflocculus and flocculus (lateral extensions of lobules VIII-X).
TS27: cerebellum anterior lobe Weak Regionally restricted 5B
TS27: cerebellum Purkinje cell layer Present Regionally restricted 5B Expression in neuropil above and around Purkinje cells, in fibres converging on the cerebellar nuclei, and in cerebellar nuclei themselves.
TS27: deep cerebellar nucleus Present Regionally restricted 5B Expression in neuropil above and around Purkinje cells, in fibres converging on the cerebellar nuclei, and in cerebellar nuclei themselves.

Specimen 5D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellar cortex Present Regionally restricted 5D Expression in lateral parts of the cerebellar cortex, correponding to lobulus simplex (lobule VI).
TS27: cerebellum vermis lobule VI Present Regionally restricted 5D Expression in lateral parts of the cerebellar cortex, correponding to lobulus simplex (lobule VI).
TS27: cerebellum vermis lobule VII Present Regionally restricted 5D Expression in lateral parts of the cerebellar cortex, correponding to Crus 2. Expression in the sulci separating them from the intervening Crus 1. Weak expression in Crus 1.
TS27: cerebellar hemisphere Present Regionally restricted 5D No expression in paraflocculus and flocculus (lateral extensions of lobules VIII-X).
TS27: flocculus Absent 5D No expression in paraflocculus and flocculus (lateral extensions of lobules VIII-X).
TS27: cerebellum Purkinje cell layer Present Regionally restricted 5D Expression in neuropil above and around Purkinje cells, in fibres converging on the cerebellar nuclei, and in cerebellar nuclei themselves.
TS27: deep cerebellar nucleus Present Regionally restricted 5D Expression in neuropil above and around Purkinje cells, in fibres converging on the cerebellar nuclei, and in cerebellar nuclei themselves.

Specimen Table 1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum molecular layer Present
TS27: cerebellum anterior lobe Ambiguous
TS27: cerebellum vermis lobule IX Ambiguous
TS27: cerebellum vermis lobule VIII Absent
TS27: cerebellum vermis lobule X Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory