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Gene Expression Data
Assay Details
Assay
Reference: J:34982 Karavanova I, et al., Transient and recurrent expression of the Egr-1 gene in epithelial and mesenchymal cells during tooth morphogenesis suggests involvement in tissue interactions and in determination of cell fate. Mech Dev. 1992 Nov;39(1-2):41-50
Assay type: RNA in situ
MGI Accession ID: MGI:5447342
Gene symbol: Egr1
Gene name: early growth response 1
Probe: p3.6
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen Not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: oral epithelium Absent

Specimen Not shown E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Absent

Specimen 1A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Weak Regionally restricted 1A/B Expression is in a few cell layers of condensing mesenchyme under the lower bud.
TS21: tooth bud Weak Regionally restricted 1A/B

Specimen 1C/D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar epithelium Present Regionally restricted 1C/D Expression is in a restricted area in the projection of dental epithelium.
TS22: lower jaw molar mesenchyme Strong 1C/D
TS22: cap stage tooth Strong Regionally restricted 1C/D

Specimen 2A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw molar mesenchyme Present Regionally restricted 2A Expression is around the bud of the second molar.
TS23: mandible Present Regionally restricted 2A Expression is in cells around Meckel's cartilage, as well as in differentiating bone cells.

Specimen 2B/C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw molar dental papilla Strong 2B/C

Specimen 2D/E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar dental papilla Strong Regionally restricted 2D/E Adjacent to the inner enamel epithelium.
TS24: lower jaw molar epithelium Present 2D/E
TS24: outer enamel epithelium Present 2D/E
TS24: stellate reticulum Present 2D/E

Specimen 3A/B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw molar dental papilla Very strong Non-Uniform 3A/B The second molar, dental follicle.
TS23: lower jaw molar mesenchyme Very strong Non-Uniform 3A/B The second molar, dental follicle.
TS23: stellate reticulum Very strong Regionally restricted 3A/B Expression is in the stellate reticulum of the second molar.

Specimen 3C/D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar mesenchyme Strong Regionally restricted 3C/D Expression is in mesenchyme surrounding the tooth germs.
TS24: lower jaw molar dental follicle Strong 3C/D
TS24: mandible Strong 3C/D
TS24: inner enamel epithelium Present Regionally restricted 3C/D Expression is in restricted areas.
TS24: outer enamel epithelium Present Regionally restricted 3C/D Expression is in restricted areas.
TS24: stellate reticulum Present 3C/D

Specimen 4A/B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw molar dental papilla Weak Regionally restricted 4A/B In the first molar cells of the dental papilla are negative in the mesial cusp and slightly labelled in the distal cusp. In the second molar there is strong expression in the mesial cusp and in a restricted area in the distal cusp.
TS26: lower jaw molar mesenchyme Present Regionally restricted 4A/B Expression is in restricted sites of dental follicle and surrounding mesenchyme.

Specimen 4C/D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lower jaw molar Present Regionally restricted 4C/D Expression is intense in first molar odontoblasts in a restricted area in the mesial cusp.
TS27: enamel organ Present Regionally restricted 4C/D Ameloblasts are heavily labelled in the distal slopes of mesial and distal cusps of the first molar.

Specimen Not shown P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: lower jaw molar Absent Absent in odontoblasts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory