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Gene Expression Data
Assay Details
Assay
Reference: J:68159 Lillevali K, et al., Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain. Mech Dev. 2001 Mar;101(1-2):217-20
Assay type: RNA in situ
MGI Accession ID: MGI:5447006
Gene symbol: Ptbp2
Gene name: polypyrimidine tract binding protein 2
Probe: brPTB cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Strong 2_brPTB
TS19: hindbrain Strong 2_brPTB
TS19: midbrain Strong 2_brPTB
Specimen 3B,D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forebrain Present Ubiquitous 3D , 3B Absent in the epithelium and interior of the choroid plexus.
TS20: hindbrain Present Ubiquitous 3D , 3B Absent in the epithelium and interior of the choroid plexus.
TS20: midbrain Present Ubiquitous 3D , 3B Absent in the epithelium and interior of the choroid plexus.
TS20: choroid plexus Absent 3D
Specimen 4B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hippocampus Very strong 4B
TS27: forebrain Very strong Regionally restricted 4B Expression is surrounding the hippocampus.
TS27: brain ependyma Absent 4B
TS27: lateral ventricle choroid plexus Absent 4B
Specimen 4D: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: forebrain Strong Regionally restricted 4D Expression is around the lateral ventricle.
TS27: brain ependyma Absent 4D
TS27: choroid plexus Absent 4D
Specimen 4F: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum Strong 4F
TS27: cerebellum external granule cell layer Strong 4F
TS27: cerebellum internal granule cell layer Strong 4F
Specimen 5C: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 5C
Specimen 5D: postnatal day 7 (more )
Note: Double labeled: red - Ptbp2; brown - Gfap (assay MGI:5447024).
Structure Level Pattern Image Note
TS28: hippocampus Present Regionally restricted 5D Expression is in neurons in the vicinity of hippocampus, absent in astrocytes.
Specimen 5G,H: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: brain ventricular layer Present Regionally restricted 5H , 5G
TS28: brain ependyma Absent 5G , 5H
Specimen 5J: postnatal day 7 (more )
Note: Double labeled: red - Ptbp2; brown - Gfap (assay MGI:5447024).
Structure Level Pattern Image Note
TS28: cerebellum Present 5J Expression throughout the cerebellum and absent in astrocytes.
Specimen 6C: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 6C
Specimen 6E: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: brain Present Ubiquitous 6E
TS28: hippocampus Present 6E
Specimen 6F: postnatal day 60 (more )
Note: Double labeled: red - Ptbp2; brown - Nefl (assay MGI:5447027).
Structure Level Pattern Image Note
TS28: cerebral cortex Present 6F
Specimen Not shown p14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong
TS28: hippocampus Strong
TS28: brain ependyma Absent
TS28: choroid plexus Absent
Specimen Not shown p21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong
TS28: hippocampus Strong
TS28: brain ependyma Absent
TS28: choroid plexus Absent
Specimen Not shown p60: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong
TS28: brain ependyma Absent
TS28: choroid plexus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory