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Gene Expression Data
Assay Details
Assay
Reference: J:68159 Lillevali K, et al., Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain. Mech Dev. 2001 Mar;101(1-2):217-20
Assay type: RNA in situ
MGI Accession ID: MGI:5446927
Gene symbol: Ptbp1
Gene name: polypyrimidine tract binding protein 1
Probe: PTB cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Present 2_PTB
TS19: hindbrain Weak 2_PTB
TS19: midbrain Weak 2_PTB
TS19: embryo Present 2_PTB
Specimen 3A,C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3C , 3A Expression is rostral and surrounds the ventricle.
TS20: forebrain Present Regionally restricted 3C , 3A Predominantly surrounding the ventricles.
TS20: midbrain Present Regionally restricted 3C , 3A Predominantly surrounding the ventricles.
TS20: 4th ventricle choroid plexus Present 3C , 3A
TS20: brain mantle layer Present Regionally restricted 3C , 3A Expression is in migrating neuroblasts.
Specimen 4A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hippocampus region Present 4A
TS27: lateral ventricle Present 4A
Specimen 4C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: lateral ventricle choroid plexus Present 4C
Specimen 4E: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Very strong 4E
TS27: cerebellum internal granule cell layer Present 4E
Specimen 5A: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Single cells 5A The majority of cerebral neurons lack expression.
Specimen 5B: postnatal day 7 (more )
Note: Double labeled: red - Ptbp1; brown - Gfap (assay MGI:5447024).
Structure Level Pattern Image Note
TS28: hippocampus region Weak 5B
Specimen 5E,F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: brain ependyma Present 5E , 5F
TS28: brain ventricular layer Present 5E , 5F
Specimen 5I: postnatal day 7 (more )
Note: Double labeled: red - Ptbp1; brown - Gfap (assay MGI:5447024).
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present Single cells 5I Expression is in neurons, absent in astrocytes.
Specimen 6A: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: choroid plexus Present 6A
Specimen 6B: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent 6B
Specimen Not showm P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent
TS28: telencephalon Absent
Specimen Not showm P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent
TS28: telencephalon Absent
Specimen Not showm P60: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: telencephalon Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory