About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:16888 Mason IJ, et al., FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev. 1994 Jan;45(1):15-30
Assay type: RNA in situ
MGI Accession ID: MGI:5446788
Gene symbol: Fgf7
Gene name: fibroblast growth factor 7
Probe: Fgf7 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: heart Present Earliest expression in the developing heart.

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber Strong Expression increased with highest levels in the developing common atrial chamber.
TS15: primitive ventricle Present Lower levels of expression in the primitive ventricle.

Specimen 2a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart atrium Strong 2a Highest levels of expression in the atrium.
TS17: primitive ventricle Present 2a Lower levels of expression in the primitive ventricle.
TS17: somite Present 2a

Specimen 2b: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart atrium Present Regionally restricted 2b
TS17: bulbus cordis Absent 2b
TS17: outflow tract Absent 2b No expression in truncus arteriosus.

Specimen 2c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present Widespread 2c Expression throughout the myocardium in both trabeculated and condensed regions.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: endocardial cushion Absent
TS17: sinus venosus Absent

Specimen 3a: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite 06 Weak 3a
TS15: somite 07 Weak 3a

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: myotome Weak Regionally restricted Low levels of expression first detected in myotomal cells in the most anterior 6 or 7 somites.

Specimen 3b: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: somite 06 Present 3b Authors report increased levels of expression in myotomes of the most anterior somites.
TS16: somite 07 Present 3b Authors report increased levels of expression in myotomes of the most anterior somites.

Specimen not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: trunk somite Present Regionally restricted Expression extended to somites 13 or 14.
TS16: myotome Strong Regionally restricted Authors report increased levels of expression in myotomes of the most anterior somites.

Specimen 3c/d: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk myotome Present Regionally restricted 3c/d Expression exclusively in longitudinally oriented myotomal cells in rostral somites, not in rounded cells in a more dorsal location.

Specimen 3e/f: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: myotome Present Regionally restricted 3e/f

Specimen 3h/k: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: myotome Present Regionally restricted 3h/k Expression confined to elongated myotomal cells of developing muscle masses. No expression in dorsal population of rounded myotomal cells.

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: myotome Present Authors report myotomal expression continues to increase until E11.5 (TS19).

Specimen 4a: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: forelimb bud Weak 4a Weak expression in proximal central region where first muscle masses condense.

Specimen 4b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: myotome Present Widespread 4b
TS20: skeletal muscle Present Regionally restricted 4b Expression in hypaxial muscles as far caudal as the thoracic region.

Specimen 4d: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk myotome Present Regionally restricted 4d Expression within somitic myotomal muscle and in a tongue of myotome extending ventrally into the somatopleure.

Specimen 4e: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: skeletal muscle Present Regionally restricted 4e Expression in brachial epaxial muscles.

Specimen 4f: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: tongue muscle Present Regionally restricted 4f

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: skeletal muscle Present Regionally restricted Expression in developing muscles of the snout and pelvis.

Specimen 4g/h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: skeletal muscle Present 4g/h
TS22: diaphragm Present 4g/h
TS22: lung mesenchyme Present 4g/h
TS22: nasal mesenchyme Present 4g/h
TS22: telencephalon ventricular layer Present Regionally restricted 4g/h Expression in ventricular zone of anterior horn of lateral ventricle of forebrain which generates the frontal cortical lobe.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tail myotome Present
TS22: limb musculature Present

Specimen 4j/k: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: skeletal muscle Absent 4j/k

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: limb musculature Present Regionally restricted Expression still observed in certain muscles of the tongue and developing muscles of the digits.
TS24: tongue muscle Present Regionally restricted Expression still observed in certain muscles of the tongue and developing muscles of the digits.

Specimen not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forebrain Absent

Specimen 5a/b: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present Regionally restricted 5a/b Expression within a restricted area of the ventricular zone of the forebrain.

Specimen 5c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present Regionally restricted 5c Expression in the ventricular zone in the region of the presumptive parietal cortex.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ganglionic eminence Present Regionally restricted Expression in the ventricular zone of the ganglionic eminence.

Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Absent

Specimen 6a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung mesenchyme Present 6a

Specimen 6b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present Regionally restricted 6b Expression in lung mesenchyme surrounding bronchiole.

Specimen 6c: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland mesenchyme Present 6c

Specimen 6d: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: duodenum Present Regionally restricted 6d Expression in the submucosa of the esophagus, stomach and duodenum.
TS24: esophagus Present Regionally restricted 6d Expression in the submucosa of the esophagus, stomach and duodenum.
TS24: stomach Present Regionally restricted 6d Expression in the submucosa of the esophagus, stomach and duodenum.
TS24: diaphragm Present Regionally restricted 6d Expression in the diaphragm, prominent within the fibrous region, but largely excluded from muscular regions.

Specimen 6e: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ileum Present Regionally restricted 6e Expression in the submucosa and in the tips of the villi.

Specimen 6f: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: diaphragm Present Regionally restricted 6f Expression in the diaphragm, prominent within the fibrous region, but largely excluded from muscular regions.

Specimen 6g: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb digit mesenchyme Present Regionally restricted 6g Expression in the external fibrous later of perichondrium, adjacent to proliferating chondrocytes.
TS24: limb musculature Present Punctate 6g Expression in some muscles of the digits.

Specimen 6h: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: rib Present Regionally restricted 6h Expression in the external fibrous layer of perichondrium.

Specimen 6i: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal mesenchyme Present Regionally restricted 6i High levels of expression in nasal region mucosa beneath the olfactory epithelium.

Specimen 6j: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: bladder Present Regionally restricted 6j Expression in bladder mesenchymal cells.

Specimen 6k: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: ureter Present Regionally restricted 6k Expression in mesenchymal cells in inner mucosal layer.

Specimen 6l: postnatal adult (more )
Structure Level Pattern Image Note
TS28: mesenchymal stroma of ovary Present Regionally restricted 6l Expression in medullary stroma of the ovary.

Specimen 6m/n: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa Present Regionally restricted 6m/n Expression in mesenchyme surrounding vibriss; no expression in root sheath and muscle of whisker follicle.

Specimen 6p/q: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dermis Present 6p/q

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted Expression in pancreatic mesenchyme.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: testis Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory