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Gene Expression Data
Assay Details
Assay
Reference: J:61349 Kanai-Azuma M, et al., Co-localization of FAM and AF-6, the mammalian homologues of Drosophila faf and canoe, in mouse eye development. Mech Dev. 2000 Mar 1;91(1-2):383-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5446778
Gene symbol: Afdn
Gene name: afadin, adherens junction formation factor
Antibody: anti-AF-6
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1C,E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: optic cup outer layer Present 1C , 1E
TS17: optic cup inner layer Present Regionally restricted 1C , 1E Expression in a single layer of cells of the inner layer immediately adjacent to the outer layer.
Specimen 1G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Strong 1G
TS21: anterior lens fiber Strong 1G Strong expression in lens subcapsular epithelial cells
TS21: neural retinal epithelium Present Regionally restricted 1G Expression in the inner portion of the ventricular layer.
Specimen 1I,K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pigmented retinal epithelium Strong 1K , 1I
TS26: retina inner nuclear layer Present Regionally restricted 1I , 1K Gradually increased expression in the inner portion of the ventricular layer (inner nuclear layer) from E13.5 to E18.5
Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Strong 2C
TS28: retina outer plexiform layer Strong 2C
TS28: photoreceptor layer Present 2C Expression in the layer of photoreceptor cell bodies.
Specimen 2G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2G
TS28: cornea stroma Absent 2G No expression in the substantia propria.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory