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Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446482
Gene symbol: Hoxd13
Gene name: homeobox D13
Probe: Hoxd13 probe17
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 3 Hoxd13 13.5 wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 3_Hoxd13 13.5 wt Expression in perichondrium and cartilage, more or less throughout entire autopod.
TS21: forelimb digit mesenchyme Strong Regionally restricted 3_Hoxd13 13.5 wt Strongest expression in perichondrium of proximal digital anlagen.
TS21: forelimb digit pre-cartilage condensation Present Regionally restricted 3_Hoxd13 13.5 wt No expression in hypertrophic chondrocytes.

Specimen 3 Hoxd13 13.5 spdh/spdh: embryonic day 13.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS21: forelimb digit mesenchyme Present Regionally restricted 3_Hoxd13 13.5 spdh/spdh hyoid arch
TS21: forelimb digit pre-cartilage condensation Present Regionally restricted 3_Hoxd13 13.5 spdh/spdh hyoid arch

Specimen 3 Hoxd13 14.5 wt: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb digit mesenchyme Present Regionally restricted 3_Hoxd13 14.5 wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
TS22: forelimb phalanx cartilage condensation Present Regionally restricted 3_Hoxd13 14.5 wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.

Specimen 3 Hoxd13 14.5 spdh/spdh: embryonic day 14.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS22: forelimb digit mesenchyme Present Regionally restricted 3_Hoxd13 14.5 spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
TS22: forelimb phalanx cartilage condensation Present Regionally restricted 3_Hoxd13 14.5 spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.

Specimen 3 Hoxd13 16.5 wt: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forelimb digit mesenchyme Present Regionally restricted 3_Hoxd13 16.5 wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
TS24: forelimb phalanx Present Regionally restricted 3_Hoxd13 16.5 wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.

Specimen 3 Hoxd13 16.5 spdh/spdh: embryonic day 16.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS24: forelimb digit mesenchyme Present Regionally restricted 3_Hoxd13 16.5 spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
TS24: forelimb phalanx Present Regionally restricted 3_Hoxd13 16.5 spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.

Specimen 3 Hoxd13 Newborn wt: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: hand bone Present Regionally restricted 3_Hoxd13 Newborn wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
TS27: hand connective tissue Present Regionally restricted 3_Hoxd13 Newborn wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.
TS27: perichondrium Present Regionally restricted 3_Hoxd13 Newborn wt Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes.

Specimen 3 Hoxd13 Newborn spdh/spdh: postnatal newborn; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS27: hand bone Present Regionally restricted 3_Hoxd13 Newborn spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes. Authors state that expression was stronger in mutant compared with wildtype.
TS27: hand connective tissue Present Regionally restricted 3_Hoxd13 Newborn spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes. Authors state that expression was stronger in mutant compared with wildtype.
TS27: perichondrium Present Regionally restricted 3_Hoxd13 Newborn spdh/spdh Expression in perichondrium and cartilage; No expression in hypertrophic chondrocytes. Authors state that expression was stronger in mutant compared with wildtype.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory