Bmp4 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type:	RNA in situ
MGI Accession ID:	MGI:5446456
Gene symbol:	Bmp4
Gene name:	bone morphogenetic protein 4

Probe:	Bmp4 cDNA5
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 2 Bmp4 11.5 wt: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: handplate	Present	Regionally restricted	2_Bmp4 11.5 wt/wt

Specimen 2 Bmp4 11.5 spdh/spdh: embryonic day 11.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS19: handplate	Present	Regionally restricted	2_Bmp4 11.5 spdh/spdh	Authors state that expression is normal.

Specimen 2 Bmp4 12.5 wt: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: hand	Present	Regionally restricted	2_Bmp4 12.5 wt/wt

Specimen 2 Bmp4 12.5 spdh/spdh: embryonic day 12.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS20: hand pre-cartilage condensation	Weak		2_Bmp4 12.5 spdh/spdh	Reduced expression in cartilaginous anlagen of digits.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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