About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446453
Gene symbol: Hoxa13
Gene name: homeobox A13
Probe: Hoxa13 probe7
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown 10.5 wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present

Specimen not shown 10.5 spdh/spdh: embryonic day 10.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted Authors report normal expression domains with respect to anterior and posterior borders, but with reduced overall area of expression compared with wildtype.

Specimen 2 Hoxa13 11.5 wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 2_Hoxa13 11.5 wt/wt

Specimen 2 Hoxa13 11.5 spdh/spdh: embryonic day 11.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 2_Hoxa13 11.5 spdh/spdh Reduced expression domain with normal anterior and posterior borders.

Specimen 2 Hoxa13 12.5 wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 2_Hoxa13 12.5 wt/wt Expression more restricted to perichondrial region of cartilaginous anlagen.

Specimen 2 Hoxa13 12.5 spdh/spdh: embryonic day 12.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 2_Hoxa13 12.5 spdh/spdh Reduced expression domain with normal anterior and posterior borders.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory