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Gene Expression Data
Assay Details
Assay
Reference: J:80954 Chapman DL, et al., Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
Assay type: RNA in situ
MGI Accession ID: MGI:5445891
Gene symbol: Nefl
Gene name: neurofilament, light polypeptide
Probe: NF-L probe
Probe preparation: Antisense RNA
Results
Specimen normal: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4e left Expression is present in the basal column.
TS17: dorsal root ganglion Present 4e left
Specimen Tbx6-mutant: embryonic day 10.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4e right Expression is present in the basal column of the axial neural tube and the two paraxial tubes.
TS17: dorsal root ganglion Present 4e right The segmental pattern is disrupted in the cervical region and more caudal region of the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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