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Gene Expression Data
Assay Details
Assay
Reference: J:80954 Chapman DL, et al., Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
Assay type: RNA in situ
MGI Accession ID: MGI:5445776
Gene symbol: Meox1
Gene name: mesenchyme homeobox 1
Probe: Mox-1 probe3
Probe preparation: Antisense RNA
Results
Specimen normal: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present 3d left
TS15: somite Present Widespread 3d left Expression is present along the entire rostral-caudal axis.

Specimen Tbx6-mutant: embryonic day 9.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Absent 3d right
TS15: somite Present Regionally restricted 3d right Expression is restricted to the most anterior somites. There is no expression in the paraxial "tubes" found in the mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory