Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trpt1tm1Dron
Name:	tRNA phosphotransferase 1; targeted mutation 1, David Ron
MGI ID:	MGI:5445769
Gene:	Trpt1  Location: Chr19:6973499-6976414 bp, + strand  Genetic Position: Chr19, 5.13 cM
Alliance:	Trpt1tm1Dron page

Germline Transmission:	Earliest citation of germline transmission: J:189412
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced exons 3 through 5. Western blot analysis confirmed the absence of protein expression in the heart. (J:189412)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trpt1 Mutation:	13 strains or lines available

Original:	J:189412 Harding HP, et al., An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation. RNA. 2008 Feb;14(2):225-32
All:	1 reference(s)