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Gene Expression Data
Assay Details
Assay
Reference: J:66536 Pinco KA, et al., alpha4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development. Mech Dev. 2001 Jan;100(1):99-103
Assay type: RNA in situ
MGI Accession ID: MGI:5444740
Gene symbol: Itga4
Gene name: integrin alpha 4
Probe: pZ5.6
Probe preparation: Antisense RNA
Assay notes: Most specimens age determined by somite counts.
Results
Specimen 1A: embryonic day 8.0 (more )
Note: 6-7 somites.
Structure Level Pattern Image Note
TS12: future brain neural crest Present Regionally restricted 1A Expression is in cells emerging from the neuroectoderm in the cranial region.
Specimen 1B: embryonic day 8.5 (more )
Note: 8 somites.
Structure Level Pattern Image Note
TS13: future midbrain Present Regionally restricted 1B Expression is in a sheet of cells extending ventrally from the neuroectoderm of the forebrain and midbrain.
TS13: future prosencephalon Present Regionally restricted 1B Expression is in a sheet of cells extending ventrally from the neuroectoderm of the forebrain and midbrain.
Specimen 1C: embryonic day 8.5 (more )
Note: 8 somites.
Structure Level Pattern Image Note
TS13: future midbrain Present Regionally restricted 1C Expression is in a sheet of cells extending ventrally from the neuroectoderm of the forebrain and midbrain.
TS13: future prosencephalon Present Regionally restricted 1C Expression is in a sheet of cells extending ventrally from the neuroectoderm of the forebrain and midbrain.
Specimen 1D: embryonic day 8.5 (more )
Note: 10 somites.
Structure Level Pattern Image Note
TS13: future brain neural crest Present Regionally restricted 1D Expression is in a stream of cells between the dorsal neuroectoderm of the midbrain and the ventral region of the first branchial arch and the optic vesicle.
TS13: head mesenchyme derived from neural crest Present Regionally restricted 1D Expression is in a stream of cells between the dorsal neuroectoderm of the midbrain and the ventral region of the first branchial arch and the optic vesicle.
Specimen 1E: embryonic day 8.5 (more )
Note: 12 somites.
Structure Level Pattern Image Note
TS13: head mesenchyme derived from neural crest Present Regionally restricted 1E Expression is in the area surrounding the optic vesicle.
Specimen 1F: embryonic day 9.0 (more )
Note: 20 somites.
Structure Level Pattern Image Note
TS14: head mesenchyme derived from neural crest Present Regionally restricted 1F Expression is in the area surrounding the optic vesicle.
TS14: otic placode Present Regionally restricted 1F Expression is in the ventral half.
TS14: septum transversum Strong Regionally restricted 1F Expression is in a small area of the septum transversum under the developing heart.
Specimen 1G: embryonic day 9.5 (more )
Note: 25 somites.
Structure Level Pattern Image Note
TS15: head mesenchyme Absent 1G
Specimen 1H: embryonic day 8.0 (more )
Note: 6-7 somites.
Structure Level Pattern Image Note
TS12: future brain neural crest Present Regionally restricted 1H Expression is in cells emerging from the neuroectoderm in the cranial region.
Specimen 1I: embryonic day 8.5 (more )
Note: 8 somites.
Structure Level Pattern Image Note
TS13: future midbrain Present Regionally restricted 1I Expression is in a sheet of cells extending ventrally from the neuroectoderm of the forebrain and midbrain.
TS13: future prosencephalon Present Regionally restricted 1I Expression is in a sheet of cells extending ventrally from the neuroectoderm of the forebrain and midbrain.
Specimen 1J: embryonic day 8.5 (more )
Note: 10 somites.
Structure Level Pattern Image Note
TS13: future brain neural crest Present Regionally restricted 1J Expression is in a stream of cells between the dorsal neuroectoderm of the midbrain and the ventral region of the first branchial arch and the optic vesicle.
TS13: head mesenchyme derived from neural crest Present Regionally restricted 1J Expression is in a stream of cells between the dorsal neuroectoderm of the midbrain and the ventral region of the first branchial arch and the optic vesicle.
Specimen 1K: embryonic day 8.5 (more )
Note: 12 somites.
Structure Level Pattern Image Note
TS13: head mesenchyme derived from neural crest Present Regionally restricted 1K Expression is in the area surrounding the optic vesicle.
Specimen 1L: embryonic day 9.0 (more )
Note: 20 somites.
Structure Level Pattern Image Note
TS14: head mesenchyme Present Regionally restricted 1L
TS14: prosencephalon Absent 1L
Specimen 2A: embryonic day 8.5 (more )
Note: 8 somites.
Structure Level Pattern Image Note
TS13: future midbrain Present Regionally restricted 2A Expression is restricted laterally.
TS13: future prosencephalon Present Regionally restricted 2A Expression is restricted laterally.
TS13: future brain neural crest Present 2A
Specimen 2D: embryonic day 9.0 (more )
Note: 20 somites.
Structure Level Pattern Image Note
TS14: head mesenchyme Present Regionally restricted 2D
TS14: prosencephalon Absent 2D
Specimen 2E: embryonic day 9.0 (more )
Note: 20 somites.
Structure Level Pattern Image Note
TS14: embryo Present Regionally restricted 2E
Specimen 2G: embryonic day 9.5 (more )
Note: 25 somites.
Structure Level Pattern Image Note
TS15: head mesenchyme Absent 2G
Specimen 2H: embryonic day 9.5 (more )
Note: 25 somites.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 2H
TS15: septum transversum Strong Regionally restricted 2H Expression is in a small area of the septum transversum under the developing heart.
Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future brain neural crest Present Regionally restricted 4A Expression is anterior to the boundary between r2 and r3.
Specimen 5A: embryonic day 9.0 (more )
Note: 20 somites.
Structure Level Pattern Image Note
TS14: septum transversum Present Regionally restricted 5A
Specimen 5B: embryonic day 9.5 (more )
Note: 25 somites.
Structure Level Pattern Image Note
TS15: heart Present Regionally restricted 5B Expression is in migrating epicardial cells on the heart.
TS15: septum transversum Present Regionally restricted 5B Expression is in migrating epicardial cells on the heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory