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Gene Expression Data
Assay Details
Assay
Reference: J:77274 Stecca B, et al., Gcm1 expression defines three stages of chorio-allantoic interaction during placental development. Mech Dev. 2002 Jul;115(1-2):27-34
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5444440
Gene symbol: Gcm1
Gene name: glial cells missing homolog 1
Reporter: lacZ
Direct Detection
Results
Specimen E9.5 - top view: embryonic day 9.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Present 1C E9.5 top As development proceeds, there is an increase in the number and area of expressing cells.

Specimen E9.5 - transversal view: embryonic day 9.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Note: crescent cross section
Structure Level Pattern Image Note
TS15: chorionic plate Present 1C E9.5 bottom Expression is present along the whole fusion surface.

Specimen E10.5 - top view: embryonic day 10.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Structure Level Pattern Image Note
TS17: labyrinthine zone Present 1C E10.5 top As development proceeds, there is an increase in the number and area of expressing cells.

Specimen E10.5 - transversal view: embryonic day 10.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Note: crescent cross section
Structure Level Pattern Image Note
TS17: chorionic plate Present 1C E10.5 bottom Expression is present along the whole fusion surface.

Specimen E12.5 - top view: embryonic day 12.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Structure Level Pattern Image Note
TS20: labyrinthine zone Present 1C E12.5 top As development proceeds, there is an increase in the number and area of expressing cells.

Specimen E12.5 - transversal view: embryonic day 12.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Note: crescent cross section
Structure Level Pattern Image Note
TS20: chorionic plate Present 1C E12.5 bottom Expression is present along the whole fusion surface.

Specimen 3B: embryonic day 8.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: chorionic plate Present Regionally restricted 3B Expression is present in trophoblast cells of the chorion.
TS13: trophectoderm Present Regionally restricted 3B Expression is present in trophoblast cells of the chorion.

Specimen 3C: embryonic day 8.75-9.0; Gcm1tm1Ral/Gcm1tm1Ral (more )
Note: coronal section
Structure Level Pattern Image Note
TS14: trophectoderm Present Regionally restricted 3C Expression is present in trophoblast cells surrounding the developing fetal vasculature.

Specimen 3D: embryonic day 8.75-9.0; Gcm1tm1Ral/Gcm1tm1Ral (more )
Note: transverse section
Structure Level Pattern Image Note
TS14: chorionic plate Present Regionally restricted 3D Expression is present in trophoblast cells of the chorion.
TS14: trophectoderm Present Regionally restricted 3D Expression is present in trophoblast cells of the chorion.

Specimen 4A: embryonic day 8.5; Gcm1tm1Ral/Gcm1tm1Ral (more )
Structure Level Pattern Image Note
TS13: chorioallantoic placenta Present Spotted 4A Expression is present in clusters of 4-8 cells, separated by non-expressing cells.

Specimen 4B: embryonic day 8.75; Gcm1tm1Ral/Gcm1tm1Ral (more )
Structure Level Pattern Image Note
TS14: chorioallantoic placenta Present Spotted 4B Expression is present in clusters.

Specimen 4C: embryonic day 8.75-9.0; Gcm1tm1Ral/Gcm1tm1Ral (more )
Structure Level Pattern Image Note
TS14: chorioallantoic placenta Present Regionally restricted 4C Expression is detected all along the chorio-allantoic interface as a continuous layer.

Specimen Not shown: embryonic day 8.75; Gcm1tm1Ral/Gcm1tm1Ral, Hsp90ab1Gt(pGT1.8geo)1Pgr/Hsp90ab1Gt(pGT1.8geo)1Pgr (more )
Structure Level Pattern Image Note
TS14: chorionic plate Present Expression is as in wild type.

Specimen Not shown: embryonic day 10.5; Gcm1tm1Ral/Gcm1tm1Ral, Hsp90ab1Gt(pGT1.8geo)1Pgr/Hsp90ab1Gt(pGT1.8geo)1Pgr (more )
Structure Level Pattern Image Note
TS17: labyrinthine zone Present Expression levels are dramatically reduced compared to those seen in wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory