Tg(AMELX-EGFP/RHOA*T19N)13Gibs
Transgene Detail
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Symbol: |
Tg(AMELX-EGFP/RHOA*T19N)13Gibs |
Name: |
transgene insertion 13, Carolyn Gibson |
MGI ID: |
MGI:5443834 |
Synonyms: |
TgAmelxEGFP-RhoADN-13, Tg(Amelx-EGFPRhoA-DN)13Gibs |
Transgene: |
Tg(AMELX-EGFP/RHOA*T19N)13Gibs Location: unknown
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Alliance: |
Tg(AMELX-EGFP/RHOA*T19N)13Gibs page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Dominant negative, Humanized sequence, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Tg(AMELX-EGFP/RHOA*T19N)13Gibs expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
RHOA (387) |
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Mutation details: The bovine promoter drives ameloblast-specific expression of an EGFP and dominant negative human RHOA (T19N) fusion. Three lines were generated (8, 2, and 13 with low, intermediate and high expression, respectively).
(J:188913)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:188913 Li Y, et al., Dental enamel structure is altered by expression of dominant negative RhoA in ameloblasts. Cells Tissues Organs. 2011;194(2-4):227-31 |
All: |
3 reference(s) |
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