Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slamf8tm1Mill
Name:	SLAM family member 8; targeted mutation 1, Millennium Pharmaceuticals Inc
MGI ID:	MGI:5442794
Synonyms:	Slamf8deltaE2-4
Gene:	Slamf8  Location: Chr1:172409325-172418135 bp, - strand  Genetic Position: Chr1, 79.99 cM, cytoband H2
Alliance:	Slamf8tm1Mill page

Germline Transmission:	Earliest citation of germline transmission: J:188963
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced exons 2 through 4. RT-PCR confirmed the absence of transcript expression in the spleen. (J:188963)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slamf8 Mutation:	14 strains or lines available

Original:	J:188963 Wang G, et al., Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages. J Immunol. 2012 Jun 15;188(12):5829-32
All:	3 reference(s)