About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:3678 Soininen R, et al., The mouse Enhancer trap locus 1 (Etl-1): a novel mammalian gene related to Drosophila and yeast transcriptional regulator genes. Mech Dev. 1992 Nov;39(1-2):111-23
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5442597
Gene symbol: Smarcad1
Gene name: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Reporter: lacZ
Direct Detection
Results
Specimen E10.0: embryonic day 10.0; Smarcad1tm1Gos/Smarcad1+ (more )
Structure Level Pattern Image Note
TS16: future hindbrain Strong
TS16: eye Weak
TS16: future midbrain Weak
TS16: spinal ganglion Weak
TS16: telencephalon Weak
TS16: future spinal cord Weak Regionally restricted Expression in spinal cord mantle and ependymal layers.
TS16: lens pit Weak Regionally restricted Expression in lens epithelium.
TS16: gut Trace
TS16: cardiac muscle tissue Absent
TS16: surface ectoderm Absent No expression in integument.

Specimen E12.5: embryonic day 12.5; Smarcad1tm1Gos/Smarcad1+ (more )
Structure Level Pattern Image Note
TS20: hindbrain Strong
TS20: integumental system Present Regionally restricted Expression in integument and hair follicles.
TS20: eye Weak
TS20: lens vesicle epithelium Weak
TS20: midbrain Weak
TS20: spinal cord mantle layer Weak
TS20: spinal cord ventricular layer Weak
TS20: spinal ganglion Weak
TS20: telencephalon Weak
TS20: gut Trace
TS20: liver Trace
TS20: cardiac muscle tissue Absent
TS20: cartilage Absent
TS20: lung Absent
TS20: vertebral cartilage condensation Absent No expression in vertebra.
TS20: skeletal muscle Absent No expression in trunk or limb muscle.
TS20: jaw primordium Absent No expression in odontoblasts.

Specimen E15.5: embryonic day 15.5; Smarcad1tm1Gos/Smarcad1+ (more )
Structure Level Pattern Image Note
TS23: hair follicle Strong
TS23: submandibular gland primordium Strong
TS23: gut epithelium Moderate
TS23: hindbrain Moderate
TS23: pigmented retinal epithelium Moderate
TS23: retina nuclear layer Moderate Regionally restricted Expression in inner and outer nuclear layers.
TS23: epidermis Moderate Regionally restricted Expression in the stratum germinativum.
TS23: lens epithelium Weak
TS23: midbrain Weak
TS23: spinal cord mantle layer Weak
TS23: spinal cord ventricular layer Weak
TS23: spinal ganglion Weak
TS23: telencephalon Weak
TS23: tooth Weak
TS23: maturing glomerular tuft Weak Low expression in glomeruli.
TS23: liver Trace
TS23: lung Trace
TS23: thymus primordium Trace
TS23: skeleton Trace Barely detectable in periosteum; no expression in long bones.
TS23: cardiac muscle tissue Absent
TS23: cranium Absent
TS23: dermis Absent
TS23: diaphragm Absent
TS23: gut mesenchyme Absent
TS23: lung mesenchyme Absent
TS23: mesenchyme of metanephros Absent
TS23: vertebra Absent
TS23: skeletal muscle Absent No expression in trunk or limb muscle.

Specimen E18.5: embryonic day 18.5; Smarcad1tm1Gos/Smarcad1+ (more )
Structure Level Pattern Image Note
TS26: cerebellum Strong
TS26: epidermis basal layer Strong
TS26: hair follicle Strong
TS26: submandibular gland Strong
TS26: tooth Strong Regionally restricted Expression in ameloblasts and odontoblasts.
TS26: gut epithelium Moderate
TS26: hippocampus Moderate
TS26: pigmented retinal epithelium Moderate
TS26: pons Moderate
TS26: retina inner nuclear layer Moderate
TS26: retina outer nuclear layer Moderate
TS26: spinal cord ventricular layer Moderate
TS26: inner ear epithelium Moderate Regionally restricted Expression in sensory epithelium.
TS26: eye Present Expression in lacrimal gland.
TS26: bronchus epithelium Weak
TS26: glomerular tuft Weak
TS26: lens epithelium Weak
TS26: lung Weak
TS26: main olfactory bulb Weak
TS26: midbrain Weak
TS26: spinal cord mantle layer Weak
TS26: spinal ganglion Weak
TS26: telencephalon Weak
TS26: liver Trace
TS26: thymus Trace
TS26: skeleton Trace Regionally restricted Barely detectable expression in periosteum; no expression in long bones.
TS26: cardiac muscle tissue Absent
TS26: cranium Absent
TS26: dental papilla Absent
TS26: dermis Absent
TS26: diaphragm Absent
TS26: gut mesenchyme Absent
TS26: limb musculature Absent
TS26: lung mesenchyme Absent
TS26: mesenchyme of metanephros Absent
TS26: vertebra Absent
TS26: vertebral axis musculature Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory