About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:46141 Hostikka SL, et al., The mouse Hoxc11 gene: genomic structure and expression pattern. Mech Dev. 1998 Jan;70(1-2):133-45
Assay type: RNA in situ
MGI Accession ID: MGI:5442134
Gene symbol: Hoxc11
Gene name: homeobox C11
Probe: Hoxc11 probe
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Assay notes: Either <35>S or <33>P was used to label the probe.
Results
Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: genitourinary system Present Regionally restricted Expression is present in the mesenchyme near the urogenital sinus.

Specimen 4B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: urogenital sinus Present Regionally restricted 4A/B Expression is present in the mesenchyme near the urogenital sinus.

Specimen 4F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lumbar vertebral cartilage condensation Present Regionally restricted 4E/F Expression is observed at the level of prevertebrae 26 and continues caudally.
TS20: vertebral cartilage condensation Present Regionally restricted 4E/F Expression is observed at the level of prevertebrae 26 and continues caudally.
TS20: cervical vertebral cartilage condensation Absent 4E/F
TS20: spinal cord Present Regionally restricted 4E/F Expression is observed at the level of prevertebrae 22 and continues caudally.
TS20: tail spinal cord Present 4E/F
TS20: dorsal root ganglion Present Regionally restricted 4E/F The anterior limit of expression is intermediate to those seen in the neural tube and prevertebrae.
TS20: nephric duct of male, mesonephric portion Strong 4E/F
TS20: paramesonephric duct Strong 4E/F
TS20: trunk mesenchyme Strong Regionally restricted 4E/F Expression is present in the mesenchyme surrounding the ventral aorta.
TS20: mesenchyme of metanephros Strong 4E/F
TS20: genital tubercle Present Regionally restricted 4E/F Expression is present in the mesenchyme, where it becomes continguous with the tail, being strongest at the groove closest to the outer epithelia as it is beginning to involute to form the anus.

Specimen 4J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lumbar vertebral cartilage condensation Present Regionally restricted 4I/J Expression is observed at the level of prevertebrae 26 and continues caudally.
TS21: vertebral cartilage condensation Present Regionally restricted 4I/J Expression is observed at the level of prevertebrae 26 and continues caudally.
TS21: cervical vertebral cartilage condensation Absent 4I/J
TS21: spinal cord Present Regionally restricted 4I/J Expression is observed at the level of prevertebrae 21 and continues caudally.
TS21: tail spinal cord Present 4I/J
TS21: dorsal root ganglion Present Regionally restricted 4I/J The anterior limit of expression is intermediate to those seen in the neural tube and prevertebrae.
TS21: nephric duct Present 4I/J
TS21: paramesonephric duct Present 4I/J
TS21: genital tubercle Strong Regionally restricted 4I/J Expression is present in the mesenchyme.
TS21: mesenchyme of metanephros Present 4I/J

Specimen 4N: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Present 4M/N
TS22: vertebral cartilage condensation Present 4M/N

Specimen 5B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Present Regionally restricted 5A/B In most posterior regions, expression is restricted to the ventral half of the neural tube.
TS23: metanephros Absent 5A/B

Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb mesenchyme Present Regionally restricted 6A/B Expression is posterior and areas of expression include the muscles.
TS20: foot mesenchyme Absent 6A/B
TS20: hindlimb epithelium Present 6A/B

Specimen Not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb mesenchyme Present Regionally restricted Expression is concentrated in the region where muscles are forming.
TS21: hindlimb musculature Present
TS21: foot mesenchyme Absent
TS21: hindlimb epithelium Present

Specimen 6F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb mesenchyme Present Regionally restricted 6E/F Expression is posterior; it is restricted to the muscles around and posterior to the ischium, pubis, femur, and fibula but not extending into the region of the tibia.
TS22: hindlimb musculature Present 6E/F
TS22: foot mesenchyme Absent 6E/F
TS22: hindlimb epidermis Present 6E/F

Specimen Not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb skin Present
TS23: hindlimb skin Present

Specimen 7D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal cortex Present Regionally restricted 7A/D Expression is detectable only in the undifferentiated mesenchyme.
TS22: mesenchyme of metanephros Present 7A/D
TS22: paramesonephric duct of male Strong 7A/D
TS22: genital tubercle Present Regionally restricted 7A/D Expression is present in the differentiating mesenchyme surrounding the urethra and mesenchyme surrounding differentiating anorectal epithelial cells.

Specimen 7E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal cortex Present Regionally restricted 7B/E Expression is detectable only in the undifferentiated mesenchyme.
TS22: mesenchyme of metanephros Present 7B/E
TS22: genital tubercle Present Regionally restricted 7B/E Expression is present in the differentiating mesenchyme surrounding the urethra and mesenchyme surrounding differentiating anorectal epithelial cells.

Specimen 7F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Present Regionally restricted 7C/F Expression is present in the mesenchyme surrounding the cartilaginous condensation and later in the musculature posterior and dorsal to the pubic bone (ischium).
TS22: tail Present Regionally restricted 7C/F Expression is present in the mesenchyme surrounding the cartilaginous condensation and later in the musculature posterior and dorsal to the pubic bone (ischium).
TS22: nephric duct of male, mesonephric portion Present 7C/F
TS22: paramesonephric duct of male Present 7C/F

Specimen 8B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nerve of pelvic urethra of male Present 8A/B Expression is present in the forming pelvic/hypograstic plexus.
TS23: urethra of male Present Regionally restricted 8A/B Expression is present in the forming urethral sphincter.
TS23: genital tubercle Present Regionally restricted 8A/B Expression is present in the mesenchyme by the prostatic region of urethra and surrounding anus. It becomes more restricted to specific muscles, in the erectile tissue and cartilaginous condensations of the os penis.
TS23: paramesonephric duct Present Regionally restricted 8A/B Expression is present in the caudal part.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory