Gene Expression Data
Assay Details
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Assay
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Reference:
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J:98114
Friedman RA, et al., Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development. Mech Dev. 2005 May;122(5):625-34
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5441103
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Antibody:
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anti-Isl1
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Detection system:
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Secondary antibody coupled to rhodamine
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Results
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Specimen
2A:
embryonic day 10.5
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: otocyst |
Present |
Regionally restricted |
2A
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Expression is shifted ventrally compared with wild type embryos, but to a lesser degree than in Eya -/- mutants.
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Specimen
2B:
(close )
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Genetic Background:
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involves: C3HeB/FeJ
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Mutant Allele(s):
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Eya1bor/Eya1bor
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: otocyst |
Weak |
Regionally restricted |
2B
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Authors report significantly fewer expressing cells.
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Analysis Tools
