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Ddit3tm2.1Dron
Targeted Allele Detail
Summary
Symbol: Ddit3tm2.1Dron
Name: DNA-damage inducible transcript 3; targeted mutation 2.1, David Ron
MGI ID: MGI:5441015
Synonyms: Chop-, CHOP::LacZ
Gene: Ddit3  Location: Chr10:127126662-127132160 bp, + strand  Genetic Position: Chr10, 74.5 cM
Alliance: Ddit3tm2.1Dron page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA NLS-lacZ cassette and a floxed PGK-Neo cassette replaced the coding region in parts of exons 3 and 4. Cre-mediated recombination removed the neo cassette. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddit3 Mutation:  20 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  84 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory