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Tg(Hoxa4-cre)2Jlzn
Transgene Detail
Summary
Symbol: Tg(Hoxa4-cre)2Jlzn
Name: transgene insertion 2, Jeffrey Lorenz Neul
MGI ID: MGI:5440715
Synonyms: HoxA4Cre, Tg(Hoxa4-cre)2Hzo
Transgene: Tg(Hoxa4-cre)2Jlzn  Location: unknown  
Alliance: Tg(Hoxa4-cre)2Jlzn page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Hoxa4-cre)2Jlzn expression driven by 1 gene
 
Mutation detailsA construct was generated that consisted of the Hoxa4 enhancer/promoter (including exon 1 and part of exon 2) with cre recombinase sequence fused in-frame with Hoxa4 at exon2, and a polyadenylation signal. The transgene was injected into pronuclei to generate two transgenic lines. Both lines were maintained and line 2 was analyzed in detail. (J:188329)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hoxa4 (species not specified)
Summary of all recombinase alleles driven by Hoxa4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:188329 Huang WH, et al., Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory