Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Bap1tm1.1Geno
Name:	Brca1 associated protein 1; targeted mutation 1.1, Genoway
MGI ID:	MGI:5439652
Synonyms:	Bap1fl
Gene:	Bap1  Location: Chr14:30973407-30981901 bp, + strand  Genetic Position: Chr14, 19.09 cM
Alliance:	Bap1tm1.1Geno page

Germline Transmission:	Earliest citation of germline transmission: J:187380
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 5 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:187380)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bap1 Mutation:	37 strains or lines available

Original:	J:187380 Dey A, et al., Loss of the tumor suppressor BAP1 causes myeloid transformation. Science. 2012 Sep 21;337(6101):1541-6
All:	5 reference(s)