About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:3293 Reaume AG, et al., Expression analysis of a Notch homologue in the mouse embryo. Dev Biol. 1992 Dec;154(2):377-87
Assay type: RNA in situ
MGI Accession ID: MGI:5439157
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5A/B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trunk unsegmented mesenchyme Strong 5A/B Strong expression is present in the presomitic mesoderm.
TS13: heart Strong 5A/B Strong expression is present in the endocardium.
TS13: dorsal aorta Strong 5A/B
TS13: head mesenchyme Present 5A/B
TS13: yolk sac mesenchyme Present 5A/B
TS13: allantois Present 5A/B The expression seen may be in the endothelial cells of forming blood vessels.
TS13: neural ectoderm Trace 5A/B Only low levels of expression were observed in the neural tube.

Specimen 5C/D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain ventricular layer Strong 5C/D There is strong expression throughout the neuroepithelium of the developing central nervous system.
TS17: future spinal cord Present Regionally restricted 5C/D There is strong expression throughout the neuroepithelium (ventricular layer) of the developing central nervous system.
TS17: dorsal root ganglion Strong 5C/D

Specimen 5E/F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain ventricular layer Present 5E/F Expression is restricted to proliferating cells in the ventricular zone.
TS20: spinal cord ventricular layer Present 5E/F Expression is restricted to proliferating cells in the ventricular zone.
TS20: blood vessel Present 5E/F Expression is present in the endothelial cells lining the vascular meningeal plexus surrounding the brain and spinal cord.
TS20: intersegmental artery Present 5E/F Expression is present in the endothelial cells.

Specimen 5H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Present 5H Expression is present in proliferating cells.
TS20: retina Present 5H Expression is present in proliferating cells.
TS20: dorsal root ganglion Present 5H
TS20: brain ventricular layer Present 5H Expression is restricted to proliferating cells in the ventricular zone.
TS20: spinal cord ventricular layer Present 5H Expression is restricted to proliferating cells in the ventricular zone.
TS20: blood vessel Present 5H Expression is present in the endothelial cells lining the vascular meningeal plexus surrounding the brain and spinal cord.
TS20: intersegmental artery Present 5H Expression is present in the endothelial cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/30/2025
MGI 6.24
The Jackson Laboratory