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Gt(ROSA)26Sortm1(CAG-flpe)Hmpr
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-flpe)Hmpr
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Haydn Prosser
MGI ID: MGI:5438836
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-flpe)Hmpr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187956
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(CAG-flpe)Hmpr expression driven by 1 gene
 
Mutation detailsAn enhanced flp (flpe) cassette containing a splice acceptor site and driven by the CAG promoter was ligated to a downstream PGK-neo cassette and inserted at the endogenous locus. (J:187956)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  944 strains or lines available
Notes
This allele has the same molecular structure as the existing Gt(ROSA)26Sor, but it was generated in the JM8F6 ES cell line derived from C57BL6/N.
References
Original:  J:187956 Ramirez-Solis R, et al., Direct Data Submission. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory