Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccl17tm2.1(cre)Ifo
Name:	C-C motif chemokine ligand 17; targeted mutation 2.1, Irmgard Foerster
MGI ID:	MGI:5438830
Synonyms:	CCl17Cre
Gene:	Ccl17  Location: Chr8:95537081-95538664 bp, + strand  Genetic Position: Chr8, 46.85 cM
Alliance:	Ccl17tm2.1(cre)Ifo page

Germline Transmission:	Earliest citation of germline transmission: J:187773
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Ccl17tm2.1(cre)Ifo expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Ccl17 (MGI:1329039)   Mutation details: A targeting construct was generated with cDNA encoding cre recombinase with nuclear localization signal and an Frt-flanked neomycin selection cassette. Homologous recombination in E14.1 ES cells inserted the cre and neo selection marker into the second exon of Ccl17. Flp expression in vitro deleted the neomycin cassette. (J:187773)

Activity:	Tissue activity of this recombinase allele
Driver:	Ccl17 (mouse) Summary of all recombinase alleles driven by Ccl17. Alliance mouse Ccl17 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccl17 Mutation:	7 strains or lines available

Original:	J:187773 Kohler T, et al., Influence of hypoxia-inducible factor 1alpha on dendritic cell differentiation and migration. Eur J Immunol. 2012 May;42(5):1226-36
All:	1 reference(s)