Tardbp Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:159888 Sephton CF, et al., TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem. 2010 Feb 26;285(9):6826-34
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5438576
Gene symbol:	Tardbp
Gene name:	TAR DNA binding protein

Antibody:	anti-TDP-43(PTG)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1A.i. lower ©

Specimen 1A.i lower: embryonic day 1.0 (more

)
Note: Two-cell embryo.

Structure	Level	Pattern	Image	Note
TS2: 2-cell stage embryo	Present		1A.i. lower

1A.i. upper ©

Specimen 1A.i upper: embryonic day 2.5 (more

)
Note: Six-cell embryo.

Structure	Level	Pattern	Image	Note
TS3: 4-8 cell stage embryo	Present		1A.i. upper

1A.ii. ©

Specimen 1A.ii: embryonic day 3.5 (more

)
Note: Blastocyst.

Structure	Level	Pattern	Image	Note
TS4: blastocyst	Present		1A.ii.

6A. a-TDP-43 ©

6A. Merge ©

Specimen 6A: embryonic day 10.5; Tardbp^{Gt(RRB030)Byg}/Tardbp⁺ (more

)
Note: Double labeled: green - Tardbp protein; red - Tardbp reporter (assay MGI:5438575).

Structure	Level	Pattern	Image	Note
TS17: future spinal cord	Present		6A. a-TDP-43 , 6A. Merge

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24