Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	S1pr1tm1Hrose
Name:	sphingosine-1-phosphate receptor 1; targeted mutation 1, Hugh Rosen
MGI ID:	MGI:5437130
Synonyms:	Edg1eGFP, Edg1-eGFP
Gene:	S1pr1  Location: Chr3:115504082-115508704 bp, - strand  Genetic Position: Chr3, 50.0 cM
Alliance:	S1pr1tm1Hrose page

Germline Transmission:	Earliest citation of germline transmission: J:187440
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion     An EGFP with a 3'loxP site was inserted downstream of and inframe with exon 2. (J:187440)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any S1pr1 Mutation:	30 strains or lines available

Original:	J:187440 Cahalan SM, et al., Actions of a picomolar short-acting S1P(1) agonist in S1P(1)-eGFP knock-in mice. Nat Chem Biol. 2011 May;7(5):254-6
All:	9 reference(s)