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Gene Expression Data
Assay Details
Assay
Reference: J:81580 Kohn MJ, et al., Dp1 is required for extra-embryonic development. Development. 2003 Apr;130(7):1295-305
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5435894
Gene symbol: Krt8
Gene name: keratin 8
Antibody: TROMA 1
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 4D: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Present 4D
TS13: trophoblast giant cell Present 4D

Specimen 4E: embryonic day 8.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Present 4E These cells are vastly underrepresented in the mutants. (BrdU labeling demonstrates they display DNA replication defects.)
TS13: trophoblast giant cell Present 4E These cells are vastly underrepresented in the mutants. (BrdU labeling demonstrates they display DNA replication defects.)

Specimen 4F: embryonic day 8.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Present 4F These cells are vastly underrepresented in the mutants. (BrdU labeling demonstrates they display DNA replication defects.)
TS13: trophoblast giant cell Present 4F These cells are vastly underrepresented in the mutants. (BrdU labeling demonstrates they display DNA replication defects.)

Specimen 5E: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: ectoplacental cone Present 5E This includes expression in the secondary trophoblast giant cells.

Specimen 5F: embryonic day 7.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS11: ectoplacental cone Present 5F This structure is abnormally small in presumptive mutants. This includes a reduction in the number of secondary trophoblast giant cells.

Specimen 5G: embryonic day 7.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS11: ectoplacental cone Present 5G This structure is abnormally small in presumptive mutants. This includes a reduction in the number of secondary trophoblast giant cells.

Specimen 5H: embryonic day 7.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS11: ectoplacental cone Present 5H This structure is abnormally small in presumptive mutants. This includes a reduction in the number of secondary trophoblast giant cells.

Specimen 6D: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: ectoplacental cone Present 6D This includes expression in the secondary trophoblast giant cells.

Specimen 6E: embryonic day 6.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS9: ectoplacental cone Present 6E This structure is abnormally small in presumptive mutants. This includes a reduction in the number of secondary trophoblast giant cells.

Specimen 6F: embryonic day 6.5; Tfdp1tm1Lili/Tfdp1tm1Lili (more )
Structure Level Pattern Image Note
TS9: ectoplacental cone Present 6F This structure is abnormally small in presumptive mutants. This includes a reduction in the number of secondary trophoblast giant cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory