Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Crx-Atoh7,-cre)60Gla
Name:	transgene insertion 60, Tom Glaser
MGI ID:	MGI:5433290
Transgene:	Tg(Crx-Atoh7,-cre)60Gla  Location: unknown
Alliance:	Tg(Crx-Atoh7,-cre)60Gla page

Strain of Origin:

(C57BL/6J x SJL/J)F2 or (B6;129-Gt(ROSA)26Sortm1Sho/J x (C57BL/6 x SJL)F1)

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Crx-Atoh7,-cre)60Gla expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Crx (MGI:1194883)   Mutation details: A BAC transgenic targeting construct containing an Atoh7-IRES-cre-FRT-amp-FRT cassette with an SV40 polyA sequence was used to target the Crx gene in BAC clone RP23-81H17 by recombineering methods in bacteria. The cassette was inserted after the ATG initiation codon in exon 2. The amp selection cassette was deleted in targeted clones. The purified BAC construct was injected into fertilized oocytes. More than 3 lines were generated and line 764 was more extensively characterized. (J:186563)

Activity:	Tissue activity of this recombinase allele
Driver:	Crx (mouse) Summary of all recombinase alleles driven by Crx. Alliance mouse Crx gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:186563 Prasov L, et al., Pushing the envelope of retinal ganglion cell genesis: Context dependent function of Math5 (Atoh7). Dev Biol. 2012 Aug 15;368(2):214-30
All:	2 reference(s)