Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Crx-cre)352Gla
Name:	transgene insertion 352, Tom Glaser
MGI ID:	MGI:5433216
Synonyms:	Crx>Cre Tg (line 352)
Transgene:	Tg(Crx-cre)352Gla  Location: unknown
Alliance:	Tg(Crx-cre)352Gla page

Strain of Origin:

(C57BL/6J x SJL/J)F2 or (B6;129-Gt(ROSA)26Sortm1Sho/J x (C57BL/6 x SJL)F1)

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Crx-cre)352Gla expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Crx   Mutation details: A construct with a 2.4 kb fragment of the Crx gene containing the promoter and proximal regulatory region driving cre cDNA followed by an SV40 polyadenylation sequence. The construct was generated from a plasmid that contained the Crx-Atoh7-IRES-cre sequence by excising the Atoh7 and IRES pieces. The purified Crx-cre transgene was injected into oocytes. 2 founders and 2 lines were obtained, crossed to GFP reporter mice, and analyzed for GFP and cre production. A representative line, 352, was analyzed in detail. (J:186563)

Activity:	Tissue activity of this recombinase allele
Driver:	Crx (species not specified) Summary of all recombinase alleles driven by Crx. Comparative matrix view of recombinase activities

In Mice Carrying this Mutation:

14 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:186563 Prasov L, et al., Pushing the envelope of retinal ganglion cell genesis: Context dependent function of Math5 (Atoh7). Dev Biol. 2012 Aug 15;368(2):214-30
All:	6 reference(s)