Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(tetO-GLI1)10Rup
Name:	transgene insertion 10, J Ruppert
MGI ID:	MGI:5432196
Synonyms:	TRE-GLi1
Transgene:	Tg(tetO-GLI1)10Rup  Location: unknown
Alliance:	Tg(tetO-GLI1)10Rup page

Strain of Origin:

(C57BL/6 x SJL)F2

Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(tetO-GLI1)10Rup expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human GLI1 (2735) Gli1  (MGI:95727)   Mutation details: The 5.7 kB transgenic construct contains a tetracycline responsive element (TRE or tetO), the minimal human cytomegalovirus promoter, and an HA-tagged wildtype human GLI1, GLI1-Kruppel family member GLI1. (J:186380)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:186380 Li X, et al., Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation. Oncogene. 2006 Jan 26;25(4):609-21
All:	1 reference(s)