Tg(Camk2a-Grin2c/itTA)12Rsp Transgene Detail MGI Mouse (MGI:5432029)

Tg(Camk2a-Grin2c/itTA)12Rsp
Transgene Detail

Summary

Symbol:	Tg(Camk2a-Grin2c/itTA)12Rsp
Name:	transgene insertion 12, Rolf Sprengel
MGI ID:	MGI:5432029
Synonyms:	Tg^CN12-itTA
Transgene:	Tg(Camk2a-Grin2c/itTA)12Rsp Location: unknown
Alliance:	Tg(Camk2a-Grin2c/itTA)12Rsp page

Transgene
origin

Strain of Origin:

(C57BL/6 x DBA/2)F1

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence, Transactivator)

Mutation:

Insertion

Tg(Camk2a-Grin2c/itTA)12Rsp expresses 1 gene

Mutation details: The 8.5 kb promoter drives expression of the first three exons of the mouse gene, including a neuron-restrictive silencer element (NRSE), fused to an improved tetracycline transactivator (itTA) with a polyadenylation signal from the human growth hormone gene. Line 10 and 12 were generated. Line 12 exhibit more forebrain expression. (J:96556, J:103689)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:103689 Shimshek DR, et al., Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors. PLoS Biol. 2005 Nov;3(11):e354
All:	5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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