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Gene Expression Data
Assay Details
Assay
Reference: J:112319 Vanden Heuvel GB, et al., Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development. Gene Expr Patterns. 2006 Dec;6(8):1000-6
Assay type: RNA in situ
MGI Accession ID: MGI:5431874
Gene symbol: Slc12a2
Gene name: solute carrier family 12, member 2
Probe: Slc12a2 cDNA3
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 1A/B
TS21: lung Present 1A/B
TS21: metanephros Present 1A/B
TS21: olfactory epithelium Present 1A/B
TS21: tooth Present 1A/B
TS21: olfactory lobe Weak 1A/B
TS21: trigeminal ganglion Weak 1A/B

Specimen 1C/D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: choroid plexus Present 1C/D
TS22: intestine Present 1C/D
TS22: lung Present 1C/D
TS22: metanephros Present 1C/D
TS22: olfactory epithelium Present 1C/D
TS22: tooth Present 1C/D

Specimen 1E/F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine Present 1E/F
TS24: lung Present 1E/F
TS24: metanephros Present 1E/F
TS24: olfactory epithelium Present 1E/F
TS24: submandibular gland Present 1E/F
TS24: central nervous system Present Regionally restricted 1E/F Expression is in the ventricular zone.

Specimen 2A/B,G: postnatal day 3 (more )
Note: (G) High magnification DIC image of boxed region in (B)
Structure Level Pattern Image Note
TS27: glomerular tuft Strong 2A/B , 2G
TS27: nephrogenic zone Weak 2A/B
TS27: renal medulla Weak Regionally restricted 2A/B Expression is in subsets of the medulla.
TS27: renal cortex Weak Regionally restricted 2A/B Expression is in medullary rays.

Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present 2C
TS22: renal vesicle Present 2C
TS22: ureteric trunk Weak Regionally restricted 2C Expression is in the ampulla of the ureteric bud.

Specimen 2D: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: s-shaped body Present 2D

Specimen 2E: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: glomerular tuft Present Regionally restricted 2E In this capillary loop stage glomerulus expression is in the center.

Specimen 2F: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: extraglomerular mesangium Present Regionally restricted 2F

Specimen 4A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung epithelium Strong Regionally restricted 4A/B Expression is in epithelium lining the large airways.
TS24: lung mesenchyme Present Regionally restricted 4A/B Expression is in developing lung tissue where airways are found and is absent in the interstitium.
TS24: blood vessel Absent 4A/B Absent in the endothelium.

Specimen 4C/D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung epithelium Present Regionally restricted 4C/D Expression is in epithelium lining the large airways.
TS24: lung mesenchyme Present Regionally restricted 4C/D Expression is in developing lung tissue where airways are found and is absent in the interstitium.

Specimen 5A/B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland Present Regionally restricted 5A/B Expression is primarily seen in cells composing the acini while and the intercalated duct is negative/weakly labeled.

Specimen 6A/B, C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestine epithelium Present Regionally restricted 6A/B , 6C Expression is in a multilayer of epithelial cells in the developing intervillus region, the epithelial cells in the villus are negative.
TS24: intestine mucosa Absent 6C , 6A/B

Specimen 7A/B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: choroid plexus Strong 7A/B Highest expression is in the ependymal cells lining the choroid plexus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory