About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:123544 Hume CR, et al., Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns. 2007 Aug;7(7):798-807
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5431532
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-myosin VI
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: saccule epithelium Present Regionally restricted Expression was detected in a small subset of cells.
Specimen 1D: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: saccule epithelium Present Regionally restricted 1D Expression was detected in the lumenal layer of the vestibular sensory epithelium.
Specimen 1H: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: saccule epithelium Present 1H
Specimen 1L: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: saccule epithelium Present 1L
Specimen 1P: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cochlea epithelium Absent 1P
Specimen 1S: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 1S Expression was detected in the organ of Corti at the basal end of the cochlea in a single row of cells adjacent to the lumen of the cochlear duct, corresponding to the inner hair cells.
Specimen 2D: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: saccule epithelium Present Regionally restricted 2D Expression was detected exclusively in the hair cell layer of the epithelium.
Specimen 2H: embryonic day 17.0 (more )
Note: Cochlea - base
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2H Expression was detected in the basal cochlea in both inner and outer hair cells.
Specimen 2L: embryonic day 17.0 (more )
Note: Cochlea - middle
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2L Expression was detected in the middle cochlea in both inner and outer hair cells.
Specimen 2P: embryonic day 17.0 (more )
Note: Cochlea - apex
Structure Level Pattern Image Note
TS25: cochlea Absent 2P Expression was not detected in the apical cochlea.
Specimen 2Q: embryonic day 17.0 (more )
Note: Double labeled: green - Myo6; red - Sox2 (assay MGI:5431543).
Structure Level Pattern Image Note
TS25: cochlea Present Regionally restricted 2Q Along the medial to lateral axis of the mid-basal cochlea, expression was detected in hair cells.
Specimen 3D: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 3D Expression was detected in vestibular hair cells.
Specimen 3H: postnatal day 2 (more )
Note: Cochlea - base
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3H Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Specimen 3L: postnatal day 2 (more )
Note: Cochlea - middle
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3L Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Specimen 3P: postnatal day 2 (more )
Note: Cochlea - apex
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 3P Expression was detected along the entire axis of the cochlea in inner and outer hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory