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Gene Expression Data
Assay Details
Assay
Reference: J:73303 Levanon D, et al., Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis. Mech Dev. 2001 Dec;109(2):413-7
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5428977
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Reporter: lacZ
Direct Detection
Results
Specimen 3b: embryonic day 14.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS22: scapula cartilage condensation Present Regionally restricted 3b Expression is in the immature cartilage of the proximal scapula.
TS22: humerus cartilage condensation Present Regionally restricted 3b Expression is in the immature cartilage of the deltoid tuberosity of the humerus.
TS22: tibia cartilage condensation Present Regionally restricted 3b Expression is in the proximal tibial epiphysis.
TS22: cartilage Present Regionally restricted 3b Expression is in the immature cartilage of the distal acromion, the proximal ulnar epiphysis, costal cartilage, and patella.

Specimen 3h: embryonic day 16.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS24: vertebra Present Regionally restricted 3h Expression is in the caudal vertebral tips. Weak expression is in the primary ossification centers of the vertebral bodies.

Specimen 4d: embryonic day 16.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS24: heart valve Present 4d

Specimen 4e: embryonic day 16.5; Runx1tm2Spe/Runx1+ (more )
Note: Sagittal dissected brain.
Structure Level Pattern Image Note
TS24: hindbrain Present Regionally restricted 4e Bilateral expression in the dorsal vagal nucleus. A region in the pontine reticular formation, dorsal vagal nucleus, and hypoglossal nucleus.

Specimen 4f: embryonic day 16.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS24: hindbrain Present Regionally restricted 4f Expression is in the dorsal vagal nucleus, hypoglossal nucleus, and nucleus ambiguus.

Specimen Not shown: embryonic day 16.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS24: embryo mesenchyme Present Regionally restricted Expression is in the septum traversum.
TS24: cornea stroma Present
TS24: genital tubercle Present
TS24: trunk Present Regionally restricted Expression is in the thoracic and abdominal midline.
TS24: ovary Present Regionally restricted Expression is in the ovarian stroma.
TS24: hindbrain Present Regionally restricted Expression is in the trigeminal motor nucleus, the facial nucleus and in bilateral rows of ventral neurons extending from the caudal hindbrain to the cranial thoracic cord.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory