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Tg(Eno2-APPSwe)#Ykk
Transgene Detail
Summary
Symbol: Tg(Eno2-APPSwe)#Ykk
Name: transgene insertion, Yong K Kim
MGI ID: MGI:5428037
Synonyms: NSE-APPsw
Transgene: Tg(Eno2-APPSwe)#Ykk  Location: unknown  
Alliance: Tg(Eno2-APPSwe)#Ykk page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Eno2-APPSwe)#Ykk expresses 1 gene
 
Mutation detailsThe neuron specific rat enolase 2 promoter was used to drive expression of the amyloid protein precursor bearing the Swedish mutation (K670N/M671L). Lines 1223-3 and 1228 were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:100955)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:184913 Kim JH, et al., Amyloid neurotoxicity is attenuated by metallothionein: dual mechanisms at work. J Neurochem. 2012 Jun;121(5):751-62
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory