Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Mpz-RAF1/ESR1)A668Ayld
Name:	transgene insertion A668, Alison Lloyd
MGI ID:	MGI:5427464
Synonyms:	RafTR, Tg(P0-Raf1/ER)A668Alyd
Transgene:	Tg(Mpz-RAF1/ESR1)A668Ayld  Location: unknown
Alliance:	Tg(Mpz-RAF1/ESR1)A668Ayld page

Strain of Origin:

C57BL/6J

Transgene Type:    Transgenic (Inducible, Inserted expressed sequence) Inducer:    tamoxifen Mutation:    Insertion   Tg(Mpz-RAF1/ESR1)A668Ayld expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human RAF1 (5894) Raf1  (MGI:97847)   Mutation details: A v-raf-leukemia viral oncogene 1 (Raf Kinase, Raf1)/ER (a tamoxifen-inducible human estrogen receptor ligand-binding domain) fusion gene was placed under the control of the rat myelin protein zero (Mpz) promoter. Line 668 was generated. (J:182703)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:182703 Napoli I, et al., A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo. Neuron. 2012 Feb 23;73(4):729-42
All:	1 reference(s)